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Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route
This paper aims to synthesize, via the sol–gel method, a biomaterial usable in the medical field. Here, the silica-PEG-quercetin system was evaluated in relation to the different concentrations of PEG (0, 6, 12, 24, 50 wt%) and quercetin (0, 5, 10, 15 wt%), respectively. In addition, Fourier Transfo...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839305/ https://www.ncbi.nlm.nih.gov/pubmed/35164244 http://dx.doi.org/10.3390/molecules27030979 |
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author | Blanco, Ignazio Latteri, Alberta Cicala, Gianluca D’Angelo, Antonio Viola, Veronica Arconati, Vincenzo Catauro, Michelina |
author_facet | Blanco, Ignazio Latteri, Alberta Cicala, Gianluca D’Angelo, Antonio Viola, Veronica Arconati, Vincenzo Catauro, Michelina |
author_sort | Blanco, Ignazio |
collection | PubMed |
description | This paper aims to synthesize, via the sol–gel method, a biomaterial usable in the medical field. Here, the silica-PEG-quercetin system was evaluated in relation to the different concentrations of PEG (0, 6, 12, 24, 50 wt%) and quercetin (0, 5, 10, 15 wt%), respectively. In addition, Fourier Transform-Infrared spectroscopy (FT-IR), Scanning Electron Microscopy (SEM), and Kirby–Bauer analyses were performed. FT-IR was used to evaluate the hybrid formation and the influence of both PEG and Quercetin in the hybrid synthesized materials, SEM was used to evaluate the morphological properties, while the Kirby–Bauer test was used to understand the ability of the materials to inhibit the growth of the assayed bacterial strains (Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecalis, and Staphylococcus aureus). |
format | Online Article Text |
id | pubmed-8839305 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-88393052022-02-13 Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route Blanco, Ignazio Latteri, Alberta Cicala, Gianluca D’Angelo, Antonio Viola, Veronica Arconati, Vincenzo Catauro, Michelina Molecules Article This paper aims to synthesize, via the sol–gel method, a biomaterial usable in the medical field. Here, the silica-PEG-quercetin system was evaluated in relation to the different concentrations of PEG (0, 6, 12, 24, 50 wt%) and quercetin (0, 5, 10, 15 wt%), respectively. In addition, Fourier Transform-Infrared spectroscopy (FT-IR), Scanning Electron Microscopy (SEM), and Kirby–Bauer analyses were performed. FT-IR was used to evaluate the hybrid formation and the influence of both PEG and Quercetin in the hybrid synthesized materials, SEM was used to evaluate the morphological properties, while the Kirby–Bauer test was used to understand the ability of the materials to inhibit the growth of the assayed bacterial strains (Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecalis, and Staphylococcus aureus). MDPI 2022-02-01 /pmc/articles/PMC8839305/ /pubmed/35164244 http://dx.doi.org/10.3390/molecules27030979 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Blanco, Ignazio Latteri, Alberta Cicala, Gianluca D’Angelo, Antonio Viola, Veronica Arconati, Vincenzo Catauro, Michelina Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route |
title | Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route |
title_full | Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route |
title_fullStr | Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route |
title_full_unstemmed | Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route |
title_short | Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route |
title_sort | antibacterial and chemical characterization of silica-quercetin-peg hybrid materials synthesized by sol–gel route |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839305/ https://www.ncbi.nlm.nih.gov/pubmed/35164244 http://dx.doi.org/10.3390/molecules27030979 |
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