Cargando…

Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route

This paper aims to synthesize, via the sol–gel method, a biomaterial usable in the medical field. Here, the silica-PEG-quercetin system was evaluated in relation to the different concentrations of PEG (0, 6, 12, 24, 50 wt%) and quercetin (0, 5, 10, 15 wt%), respectively. In addition, Fourier Transfo...

Descripción completa

Detalles Bibliográficos
Autores principales: Blanco, Ignazio, Latteri, Alberta, Cicala, Gianluca, D’Angelo, Antonio, Viola, Veronica, Arconati, Vincenzo, Catauro, Michelina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839305/
https://www.ncbi.nlm.nih.gov/pubmed/35164244
http://dx.doi.org/10.3390/molecules27030979
_version_ 1784650337503674368
author Blanco, Ignazio
Latteri, Alberta
Cicala, Gianluca
D’Angelo, Antonio
Viola, Veronica
Arconati, Vincenzo
Catauro, Michelina
author_facet Blanco, Ignazio
Latteri, Alberta
Cicala, Gianluca
D’Angelo, Antonio
Viola, Veronica
Arconati, Vincenzo
Catauro, Michelina
author_sort Blanco, Ignazio
collection PubMed
description This paper aims to synthesize, via the sol–gel method, a biomaterial usable in the medical field. Here, the silica-PEG-quercetin system was evaluated in relation to the different concentrations of PEG (0, 6, 12, 24, 50 wt%) and quercetin (0, 5, 10, 15 wt%), respectively. In addition, Fourier Transform-Infrared spectroscopy (FT-IR), Scanning Electron Microscopy (SEM), and Kirby–Bauer analyses were performed. FT-IR was used to evaluate the hybrid formation and the influence of both PEG and Quercetin in the hybrid synthesized materials, SEM was used to evaluate the morphological properties, while the Kirby–Bauer test was used to understand the ability of the materials to inhibit the growth of the assayed bacterial strains (Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecalis, and Staphylococcus aureus).
format Online
Article
Text
id pubmed-8839305
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-88393052022-02-13 Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route Blanco, Ignazio Latteri, Alberta Cicala, Gianluca D’Angelo, Antonio Viola, Veronica Arconati, Vincenzo Catauro, Michelina Molecules Article This paper aims to synthesize, via the sol–gel method, a biomaterial usable in the medical field. Here, the silica-PEG-quercetin system was evaluated in relation to the different concentrations of PEG (0, 6, 12, 24, 50 wt%) and quercetin (0, 5, 10, 15 wt%), respectively. In addition, Fourier Transform-Infrared spectroscopy (FT-IR), Scanning Electron Microscopy (SEM), and Kirby–Bauer analyses were performed. FT-IR was used to evaluate the hybrid formation and the influence of both PEG and Quercetin in the hybrid synthesized materials, SEM was used to evaluate the morphological properties, while the Kirby–Bauer test was used to understand the ability of the materials to inhibit the growth of the assayed bacterial strains (Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecalis, and Staphylococcus aureus). MDPI 2022-02-01 /pmc/articles/PMC8839305/ /pubmed/35164244 http://dx.doi.org/10.3390/molecules27030979 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Blanco, Ignazio
Latteri, Alberta
Cicala, Gianluca
D’Angelo, Antonio
Viola, Veronica
Arconati, Vincenzo
Catauro, Michelina
Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route
title Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route
title_full Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route
title_fullStr Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route
title_full_unstemmed Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route
title_short Antibacterial and Chemical Characterization of Silica-Quercetin-PEG Hybrid Materials Synthesized by Sol–Gel Route
title_sort antibacterial and chemical characterization of silica-quercetin-peg hybrid materials synthesized by sol–gel route
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839305/
https://www.ncbi.nlm.nih.gov/pubmed/35164244
http://dx.doi.org/10.3390/molecules27030979
work_keys_str_mv AT blancoignazio antibacterialandchemicalcharacterizationofsilicaquercetinpeghybridmaterialssynthesizedbysolgelroute
AT latterialberta antibacterialandchemicalcharacterizationofsilicaquercetinpeghybridmaterialssynthesizedbysolgelroute
AT cicalagianluca antibacterialandchemicalcharacterizationofsilicaquercetinpeghybridmaterialssynthesizedbysolgelroute
AT dangeloantonio antibacterialandchemicalcharacterizationofsilicaquercetinpeghybridmaterialssynthesizedbysolgelroute
AT violaveronica antibacterialandchemicalcharacterizationofsilicaquercetinpeghybridmaterialssynthesizedbysolgelroute
AT arconativincenzo antibacterialandchemicalcharacterizationofsilicaquercetinpeghybridmaterialssynthesizedbysolgelroute
AT catauromichelina antibacterialandchemicalcharacterizationofsilicaquercetinpeghybridmaterialssynthesizedbysolgelroute