Cargando…

Ion Mobility Mass Spectrometry Reveals Rare Sialylated Glycosphingolipid Structures in Human Cerebrospinal Fluid

Gangliosides (GGs) represent an important class of biomolecules associated with the central nervous system (CNS). In view of their special role at a CNS level, GGs are valuable diagnostic markers and prospective therapeutic agents. By ion mobility separation mass spectrometry (IMS MS), recently impl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sarbu, Mirela, Fabris, Dragana, Vukelić, Željka, Clemmer, David E., Zamfir, Alina D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839488/ https://www.ncbi.nlm.nih.gov/pubmed/35164008 http://dx.doi.org/10.3390/molecules27030743

Ejemplares similares

Identification and Structural Characterization of Novel Chondroitin/Dermatan Sulfate Hexassacharide Domains in Human Decorin by Ion Mobility Tandem Mass Spectrometry
por: Sarbu, Mirela, et al.
Publicado: (2022)

Gangliosides as Biomarkers of Human Brain Diseases: Trends in Discovery and Characterization by High-Performance Mass Spectrometry
por: Sarbu, Mirela, et al.
Publicado: (2022)

Ganglioside Composition Distinguishes Anaplastic Ganglioglioma Tumor Tissue from Peritumoral Brain Tissue: Complementary Mass Spectrometry and Thin-Layer Chromatography Evidence
por: Fabris, Dragana, et al.
Publicado: (2021)

Separation of Sialylated Glycan Isomers by Differential Mobility Spectrometry
por: Lane, Catherine S., et al.
Publicado: (2019)

Exploration of human cerebrospinal fluid: A large proteome dataset revealed by trapped ion mobility time-of-flight mass spectrometry
por: Macron, Charlotte, et al.
Publicado: (2020)

Enhancing the sialylation of recombinant EPO produced in CHO cells via the inhibition of glycosphingolipid biosynthesis
por: Kwak, Chan-Yeong, et al.
Publicado: (2017)

Single Cerebral Organoid Mass Spectrometry of Cell-Specific Protein and Glycosphingolipid Traits
por: Nezvedová, Markéta, et al.
Publicado: (2023)

High-Resolution Tandem Mass Spectrometry Identifies a Particular Ganglioside Pattern in Early Diabetic Kidney Disease of Type 2 Diabetes Mellitus Patients
por: Suteanu-Simulescu, Anca, et al.
Publicado: (2022)

Cerebrospinal fluid proteome evaluation in major depressive disorder by mass spectrometry
por: Franzen, Avery D., et al.
Publicado: (2020)

Quantitative Measurement of Cerebrospinal Fluid Amyloid-β Species by Mass Spectrometry
por: Seino, Yusuke, et al.
Publicado: (2021)

Investigation of Dendriplexes by Ion Mobility-Mass Spectrometry
por: Leriche, Emma-Dune, et al.
Publicado: (2014)

Developments in tandem ion mobility mass spectrometry
por: Eldrid, Charles, et al.
Publicado: (2020)

Mass Spectrometric Analysis of Glycosphingolipid Antigens
por: Yin, Alexandra Bili, et al.
Publicado: (2013)

Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer’s Disease
por: Watson, Caroline M., et al.
Publicado: (2023)

Ion Mobility-Mass Spectrometry: Time-Dispersive Instrumentation
por: May, Jody C., et al.
Publicado: (2014)

Recommendations for reporting ion mobility Mass Spectrometry measurements
por: Gabelica, Valérie, et al.
Publicado: (2019)

Targeted mass spectrometry to quantify brain-derived cerebrospinal fluid biomarkers in Alzheimer’s disease
por: Zhou, Maotian, et al.
Publicado: (2020)

Identification of cerebrospinal fluid metabolites as biomarkers for neurobrucellosis by liquid chromatography-mass spectrometry approach
por: Yang, Hao, et al.
Publicado: (2022)

Exploratory mass spectrometry of cerebrospinal fluid from persons with autopsy-confirmed LATE-NC
por: Gal, Jozsef, et al.
Publicado: (2023)

Mobility-Resolved Ion Selection in Uniform Drift Field Ion Mobility Spectrometry/Mass Spectrometry: Dynamic Switching in Structures for Lossless Ion Manipulations
por: Webb, Ian K., et al.
Publicado: (2014)

Comprehensive Identification of Glycosphingolipids in Human Plasma Using Hydrophilic Interaction Liquid Chromatography—Electrospray Ionization Mass Spectrometry
por: Hořejší, Karel, et al.
Publicado: (2021)

Prediction of peptide drift time in ion mobility-mass spectrometry
por: Wang, Bing, et al.
Publicado: (2009)

Applications of Ion Mobility-Mass Spectrometry in Carbohydrate Chemistry and Glycobiology
por: Mu, Yuqing, et al.
Publicado: (2018)

Ion mobility mass spectrometry for the study of mycobacterial mycolic acids
por: Liu, Yi, et al.
Publicado: (2023)

Advances in ion mobility spectrometry–mass spectrometry reveal key insights into amyloid assembly()
por: Woods, L.A., et al.
Publicado: (2013)

Probing Polyester Branching by Hybrid Trapped Ion-Mobility Spectrometry–Tandem Mass Spectrometry
por: Voeten, Robert L. C., et al.
Publicado: (2021)

Gas Chromatography-Mass Spectrometry-Based Metabolic Profiling of Cerebrospinal Fluid from Epileptic Dogs
por: HASEGAWA, Tetsuya, et al.
Publicado: (2013)

Cerebrospinal Fluid of Preeclamptic and Normotensive Pregnant Women Compared to Nonpregnant Women Analyzed with Mass Spectrometry
por: Güzel, Coşkun, et al.
Publicado: (2020)

Lipidomics of Glycosphingolipids
por: Farwanah, Hany, et al.
Publicado: (2012)

Experimental Evaluation and Optimization of Structures for Lossless Ion Manipulations for Ion Mobility Spectrometry with Time-of-Flight Mass Spectrometry
por: Webb, Ian K., et al.
Publicado: (2014)

Adduct Ions as Diagnostic Probes of Metallosupramolecular Complexes Using Ion Mobility Mass Spectrometry
por: Geue, Niklas, et al.
Publicado: (2023)

Ion Mobility Spectrometry-Mass Spectrometry of Intrinsically Unfolded Proteins: Trying to Put Order into Disorder
por: Knapman, T. W, et al.
Publicado: (2013)

Integrating the potential of ion mobility spectrometry-mass spectrometry in the separation and structural characterisation of lipid isomers
por: Camunas-Alberca, Sandra M., et al.
Publicado: (2023)

Uncovering per- and polyfluoroalkyl substances (PFAS) with nontargeted ion mobility spectrometry–mass spectrometry analyses
por: Kirkwood-Donelson, Kaylie I., et al.
Publicado: (2023)

Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides
por: Miller, Rebecca L., et al.
Publicado: (2020)

Evaluation for Ion Heating of H2A-H2B Dimer in Ion Mobility Spectrometry–Mass Spectrometry
por: Saikusa, Kazumi, et al.
Publicado: (2023)

Clinical Mass Spectrometry Discovered Human IgG Sialylation as a Potential Biosignature for Kidney Function
por: Kao, Chih-Chin, et al.
Publicado: (2021)

N-acetylaspartic acid in cerebrospinal fluid of multiple sclerosis patients determined by gas-chromatography-mass spectrometry
por: Jasperse, Bas, et al.
Publicado: (2007)

Improved Differential Diagnosis of Alzheimer’s Disease by Integrating ELISA and Mass Spectrometry-Based Cerebrospinal Fluid Biomarkers
por: Khoonsari, Payam Emami, et al.
Publicado: (2019)

Effect of Humidity on the Mobilities of Small Ions in Ion Mobility Spectrometry
por: Wolańska, Izabela, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_3ossu2ll900f70djrlqk8rscab