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The Biological Fate of Pharmaceutical Excipient β-Cyclodextrin: Pharmacokinetics, Tissue Distribution, Excretion, and Metabolism of β-Cyclodextrin in Rats

β-cyclodextrin has a unique annular hollow ultrastructure that allows encapsulation of various poorly water-soluble drugs in the resulting cavity, thereby increasing drug stability. As a bioactive molecule, the metabolism of β-cyclodextrin is mainly completed by the flora in the colon, which can int...

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Detalles Bibliográficos
Autores principales: Mu, Kunqian, Jiang, Kaiwen, Wang, Yue, Zhao, Zihan, Cang, Song, Bi, Kaishun, Li, Qing, Liu, Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839615/
https://www.ncbi.nlm.nih.gov/pubmed/35164401
http://dx.doi.org/10.3390/molecules27031138

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