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The Biological Fate of Pharmaceutical Excipient β-Cyclodextrin: Pharmacokinetics, Tissue Distribution, Excretion, and Metabolism of β-Cyclodextrin in Rats
β-cyclodextrin has a unique annular hollow ultrastructure that allows encapsulation of various poorly water-soluble drugs in the resulting cavity, thereby increasing drug stability. As a bioactive molecule, the metabolism of β-cyclodextrin is mainly completed by the flora in the colon, which can int...
Autores principales: | Mu, Kunqian, Jiang, Kaiwen, Wang, Yue, Zhao, Zihan, Cang, Song, Bi, Kaishun, Li, Qing, Liu, Ran |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839615/ https://www.ncbi.nlm.nih.gov/pubmed/35164401 http://dx.doi.org/10.3390/molecules27031138 |
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