Independent risk factors of COVID-19 pneumonia in vaccinated Mexican adults

OBJECTIVES: To evaluate host factors associated with the risk of coronavirus disease 2019 (COVID-19) pneumonia in vaccinated adults. METHODS: A cohort study was conducted in Mexico, and data from 1607 adults with confirmed illness, with a positive history of COVID-19 vaccination, were analyzed. Risk...

Descripción completa

Detalles Bibliográficos
Autores principales: Murillo-Zamora, Efrén, Sánchez-Piña, Ramón Alberto, Trujillo, Xóchitl, Huerta, Miguel, Ríos-Silva, Mónica, Mendoza-Cano, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839797/
https://www.ncbi.nlm.nih.gov/pubmed/35167967
http://dx.doi.org/10.1016/j.ijid.2022.02.003
Descripción
Sumario:OBJECTIVES: To evaluate host factors associated with the risk of coronavirus disease 2019 (COVID-19) pneumonia in vaccinated adults. METHODS: A cohort study was conducted in Mexico, and data from 1607 adults with confirmed illness, with a positive history of COVID-19 vaccination, were analyzed. Risk ratios (RR) and 95% confidence intervals (CI) were computed as a measure of the significance of the associations between putative risk factors and the prevalence of COVID-19 pneumonia in vaccinated subjects. RESULTS: The overall risk of pneumonia was 1.98 per 1000 person-days. In the multiple regression analysis, older subjects, those with a history of smoking (current), obesity, and type 2 diabetes mellitus were at increased risk of pneumonia. CONCLUSIONS: Our results suggest that the effectiveness of COVID-19 vaccines may be reduced in a subset of adults who are older aged, smokers, obese, or have type 2 diabetes mellitus.

Ejemplares similares