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2-Hydroxyestradiol Overcomes Mesenchymal Stem Cells-Mediated Platinum Chemoresistance in Ovarian Cancer Cells in an ERK-Independent Fashion

Ovarian cancer (OC) is the second most common type of gynecological malignancy. Platinum (Pt)-based chemotherapy is the standard of care for OC, but toxicity and acquired chemoresistance has proven challenging. Recently, we reported that sensitivity to platinum was significantly reduced in a co-cult...

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Detalles Bibliográficos
Autores principales: Khamaisi, Hazem, Mahmoud, Hatem, Mahajna, Jamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839885/
https://www.ncbi.nlm.nih.gov/pubmed/35164068
http://dx.doi.org/10.3390/molecules27030804

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