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Advances in Chemical Composition, Extraction Techniques, Analytical Methods, and Biological Activity of Astragali Radix

Astragali Radix (AR) is one of the well-known traditional Chinese medicines with a long history of medical use and a wide range of clinical applications. AR contains a variety of chemical constituents which can be classified into the following categories: polysaccharides, saponins, flavonoids, amino...

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Autores principales: Chang, Xiangna, Chen, Xuefeng, Guo, Yuxi, Gong, Pin, Pei, Shuya, Wang, Danni, Wang, Peipei, Wang, Mengrao, Chen, Fuxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839891/
https://www.ncbi.nlm.nih.gov/pubmed/35164321
http://dx.doi.org/10.3390/molecules27031058
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author Chang, Xiangna
Chen, Xuefeng
Guo, Yuxi
Gong, Pin
Pei, Shuya
Wang, Danni
Wang, Peipei
Wang, Mengrao
Chen, Fuxin
author_facet Chang, Xiangna
Chen, Xuefeng
Guo, Yuxi
Gong, Pin
Pei, Shuya
Wang, Danni
Wang, Peipei
Wang, Mengrao
Chen, Fuxin
author_sort Chang, Xiangna
collection PubMed
description Astragali Radix (AR) is one of the well-known traditional Chinese medicines with a long history of medical use and a wide range of clinical applications. AR contains a variety of chemical constituents which can be classified into the following categories: polysaccharides, saponins, flavonoids, amino acids, and trace elements. There are several techniques to extract these constituents, of which microwave-assisted, enzymatic, aqueous, ultrasonic and reflux extraction are the most used. Several methods such as spectroscopy, capillary electrophoresis and various chromatographic methods have been developed to identify and analyze AR. Meanwhile, this paper also summarizes the biological activities of AR, such as anti-inflammatory, antioxidant, antitumor and antiviral activities. It is expected to provide theoretical support for the better development and utilization of AR.
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spelling pubmed-88398912022-02-13 Advances in Chemical Composition, Extraction Techniques, Analytical Methods, and Biological Activity of Astragali Radix Chang, Xiangna Chen, Xuefeng Guo, Yuxi Gong, Pin Pei, Shuya Wang, Danni Wang, Peipei Wang, Mengrao Chen, Fuxin Molecules Review Astragali Radix (AR) is one of the well-known traditional Chinese medicines with a long history of medical use and a wide range of clinical applications. AR contains a variety of chemical constituents which can be classified into the following categories: polysaccharides, saponins, flavonoids, amino acids, and trace elements. There are several techniques to extract these constituents, of which microwave-assisted, enzymatic, aqueous, ultrasonic and reflux extraction are the most used. Several methods such as spectroscopy, capillary electrophoresis and various chromatographic methods have been developed to identify and analyze AR. Meanwhile, this paper also summarizes the biological activities of AR, such as anti-inflammatory, antioxidant, antitumor and antiviral activities. It is expected to provide theoretical support for the better development and utilization of AR. MDPI 2022-02-04 /pmc/articles/PMC8839891/ /pubmed/35164321 http://dx.doi.org/10.3390/molecules27031058 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Chang, Xiangna
Chen, Xuefeng
Guo, Yuxi
Gong, Pin
Pei, Shuya
Wang, Danni
Wang, Peipei
Wang, Mengrao
Chen, Fuxin
Advances in Chemical Composition, Extraction Techniques, Analytical Methods, and Biological Activity of Astragali Radix
title Advances in Chemical Composition, Extraction Techniques, Analytical Methods, and Biological Activity of Astragali Radix
title_full Advances in Chemical Composition, Extraction Techniques, Analytical Methods, and Biological Activity of Astragali Radix
title_fullStr Advances in Chemical Composition, Extraction Techniques, Analytical Methods, and Biological Activity of Astragali Radix
title_full_unstemmed Advances in Chemical Composition, Extraction Techniques, Analytical Methods, and Biological Activity of Astragali Radix
title_short Advances in Chemical Composition, Extraction Techniques, Analytical Methods, and Biological Activity of Astragali Radix
title_sort advances in chemical composition, extraction techniques, analytical methods, and biological activity of astragali radix
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8839891/
https://www.ncbi.nlm.nih.gov/pubmed/35164321
http://dx.doi.org/10.3390/molecules27031058
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