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Preparation of Deuterium Labeled Compounds by Pd/C-Al-D(2)O Facilitated Selective H-D Exchange Reactions
The chemo/regioselective H-D exchange of amino acids and synthetic building blocks by an environmentally benign Pd/C-Al-D(2)O catalytic system is described. Due to the importance of isotope labeled compounds in medicinal chemistry and structural biology, notably their use as improved drug candidates...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840159/ https://www.ncbi.nlm.nih.gov/pubmed/35163883 http://dx.doi.org/10.3390/molecules27030614 |