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The prognostic and predictive value of ESR1 fusion gene transcripts in primary breast cancer

BACKGROUND: In breast cancer (BC), recurrent fusion genes of estrogen receptor alpha (ESR1) and AKAP12, ARMT1 and CCDC170 have been reported. In these gene fusions the ligand binding domain of ESR1 has been replaced by the transactivation domain of the fusion partner constitutively activating the re...

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Detalles Bibliográficos
Autores principales:	Vitale, Silvia R., Ruigrok-Ritstier, Kirsten, Timmermans, A. Mieke, Foekens, Renée, Trapman-Jansen, Anita M. A. C., Beaufort, Corine M., Vigneri, Paolo, Sleijfer, Stefan, Martens, John W. M., Sieuwerts, Anieta M., Jansen, Maurice P. H. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840267/ https://www.ncbi.nlm.nih.gov/pubmed/35151276 http://dx.doi.org/10.1186/s12885-022-09265-1

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