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Synthetic Diphenylacetylene-Based Retinoids Induce DNA Damage in Chinese Hamster Ovary Cells without Altering Viability

All-trans-retinoic acid (ATRA), the active metabolite of vitamin A, plays a pivotal role in cell differentiation, proliferation and embryonic development. It is an effective therapy for dermatological disorders and malignancies. ATRA is prone to isomerization and oxidation, which can affect its acti...

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Detalles Bibliográficos
Autores principales:	Hudhud, Lina, Chisholm, David R., Whiting, Andrew, Steib, Anita, Pohóczky, Krisztina, Kecskés, Angéla, Szőke, Éva, Helyes, Zsuzsanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840491/ https://www.ncbi.nlm.nih.gov/pubmed/35164242 http://dx.doi.org/10.3390/molecules27030977

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