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The Role of Minerals in the Optimal Functioning of the Immune System

Minerals fulfil a wide variety of functions in the optimal functioning of the immune system. This review reports on the minerals that are essential for the immune system’s function and inflammation regulation. We also discuss nutritional aspects of optimized mineral supply. The supply of minerals is...

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Autores principales: Weyh, Christopher, Krüger, Karsten, Peeling, Peter, Castell, Lindy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840645/
https://www.ncbi.nlm.nih.gov/pubmed/35277003
http://dx.doi.org/10.3390/nu14030644
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author Weyh, Christopher
Krüger, Karsten
Peeling, Peter
Castell, Lindy
author_facet Weyh, Christopher
Krüger, Karsten
Peeling, Peter
Castell, Lindy
author_sort Weyh, Christopher
collection PubMed
description Minerals fulfil a wide variety of functions in the optimal functioning of the immune system. This review reports on the minerals that are essential for the immune system’s function and inflammation regulation. We also discuss nutritional aspects of optimized mineral supply. The supply of minerals is important for the optimal function of the innate immune system as well as for components of adaptive immune defense; this involves defense mechanisms against pathogens in addition to the long-term balance of pro- and anti-inflammatory regulation. Generally, a balanced diet is sufficient to supply the required balance of minerals to help support the immune system. Although a mineral deficiency is rare, there are nevertheless at-risk groups who should pay attention to ensure they are receiving a sufficient supply of minerals such as magnesium, zinc, copper, iron, and selenium. A deficiency in any of these minerals could temporarily reduce immune competence, or even disrupt systemic inflammation regulation in the long term. Therefore, knowledge of the mechanisms and supply of these minerals is important. In exceptional cases, a deficiency should be compensated by supplementation; however, supplement over-consumption may be negative to the immune system, and should be avoided. Accordingly, any supplementation should be medically clarified and should only be administered in prescribed concentrations.
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spelling pubmed-88406452022-02-13 The Role of Minerals in the Optimal Functioning of the Immune System Weyh, Christopher Krüger, Karsten Peeling, Peter Castell, Lindy Nutrients Review Minerals fulfil a wide variety of functions in the optimal functioning of the immune system. This review reports on the minerals that are essential for the immune system’s function and inflammation regulation. We also discuss nutritional aspects of optimized mineral supply. The supply of minerals is important for the optimal function of the innate immune system as well as for components of adaptive immune defense; this involves defense mechanisms against pathogens in addition to the long-term balance of pro- and anti-inflammatory regulation. Generally, a balanced diet is sufficient to supply the required balance of minerals to help support the immune system. Although a mineral deficiency is rare, there are nevertheless at-risk groups who should pay attention to ensure they are receiving a sufficient supply of minerals such as magnesium, zinc, copper, iron, and selenium. A deficiency in any of these minerals could temporarily reduce immune competence, or even disrupt systemic inflammation regulation in the long term. Therefore, knowledge of the mechanisms and supply of these minerals is important. In exceptional cases, a deficiency should be compensated by supplementation; however, supplement over-consumption may be negative to the immune system, and should be avoided. Accordingly, any supplementation should be medically clarified and should only be administered in prescribed concentrations. MDPI 2022-02-02 /pmc/articles/PMC8840645/ /pubmed/35277003 http://dx.doi.org/10.3390/nu14030644 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Weyh, Christopher
Krüger, Karsten
Peeling, Peter
Castell, Lindy
The Role of Minerals in the Optimal Functioning of the Immune System
title The Role of Minerals in the Optimal Functioning of the Immune System
title_full The Role of Minerals in the Optimal Functioning of the Immune System
title_fullStr The Role of Minerals in the Optimal Functioning of the Immune System
title_full_unstemmed The Role of Minerals in the Optimal Functioning of the Immune System
title_short The Role of Minerals in the Optimal Functioning of the Immune System
title_sort role of minerals in the optimal functioning of the immune system
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840645/
https://www.ncbi.nlm.nih.gov/pubmed/35277003
http://dx.doi.org/10.3390/nu14030644
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