Cargando…

Zingiber officinale var. rubrum: Red Ginger’s Medicinal Uses

Zingiber officinale var. rubrum (red ginger) is widely used in traditional medicine in Asia. Unlike other gingers, it is not used as a spice in cuisines. To date, a total of 169 chemical constituents have been reported from red ginger. The constituents include vanilloids, monoterpenes, sesquiterpene...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Shiming, Kou, Xuefang, Zhao, Hui, Mak, Kit-Kay, Balijepalli, Madhu Katyayani, Pichika, Mallikarjuna Rao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840670/
https://www.ncbi.nlm.nih.gov/pubmed/35164040
http://dx.doi.org/10.3390/molecules27030775
_version_ 1784650677287387136
author Zhang, Shiming
Kou, Xuefang
Zhao, Hui
Mak, Kit-Kay
Balijepalli, Madhu Katyayani
Pichika, Mallikarjuna Rao
author_facet Zhang, Shiming
Kou, Xuefang
Zhao, Hui
Mak, Kit-Kay
Balijepalli, Madhu Katyayani
Pichika, Mallikarjuna Rao
author_sort Zhang, Shiming
collection PubMed
description Zingiber officinale var. rubrum (red ginger) is widely used in traditional medicine in Asia. Unlike other gingers, it is not used as a spice in cuisines. To date, a total of 169 chemical constituents have been reported from red ginger. The constituents include vanilloids, monoterpenes, sesquiterpenes, diterpenes, flavonoids, amino acids, etc. Red ginger has many therapeutic roles in various diseases, including inflammatory diseases, vomiting, rubella, atherosclerosis, tuberculosis, growth disorders, and cancer. Scientific evidence suggests that red ginger exhibits immunomodulatory, antihypertensive, antihyperlipidemic, antihyperuricemic, antimicrobial, and cytotoxic activities. These biological activities are the underlying causes of red ginger’s therapeutic benefits. In addition, there have been few reports on adverse side effects of red ginger. This review aims to provide insights in terms the bioactive constituents and their biosynthesis, biological activities, molecular mechanisms, pharmacokinetics, and qualitative and quantitative analysis of red ginger.
format Online
Article
Text
id pubmed-8840670
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-88406702022-02-13 Zingiber officinale var. rubrum: Red Ginger’s Medicinal Uses Zhang, Shiming Kou, Xuefang Zhao, Hui Mak, Kit-Kay Balijepalli, Madhu Katyayani Pichika, Mallikarjuna Rao Molecules Review Zingiber officinale var. rubrum (red ginger) is widely used in traditional medicine in Asia. Unlike other gingers, it is not used as a spice in cuisines. To date, a total of 169 chemical constituents have been reported from red ginger. The constituents include vanilloids, monoterpenes, sesquiterpenes, diterpenes, flavonoids, amino acids, etc. Red ginger has many therapeutic roles in various diseases, including inflammatory diseases, vomiting, rubella, atherosclerosis, tuberculosis, growth disorders, and cancer. Scientific evidence suggests that red ginger exhibits immunomodulatory, antihypertensive, antihyperlipidemic, antihyperuricemic, antimicrobial, and cytotoxic activities. These biological activities are the underlying causes of red ginger’s therapeutic benefits. In addition, there have been few reports on adverse side effects of red ginger. This review aims to provide insights in terms the bioactive constituents and their biosynthesis, biological activities, molecular mechanisms, pharmacokinetics, and qualitative and quantitative analysis of red ginger. MDPI 2022-01-25 /pmc/articles/PMC8840670/ /pubmed/35164040 http://dx.doi.org/10.3390/molecules27030775 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Zhang, Shiming
Kou, Xuefang
Zhao, Hui
Mak, Kit-Kay
Balijepalli, Madhu Katyayani
Pichika, Mallikarjuna Rao
Zingiber officinale var. rubrum: Red Ginger’s Medicinal Uses
title Zingiber officinale var. rubrum: Red Ginger’s Medicinal Uses
title_full Zingiber officinale var. rubrum: Red Ginger’s Medicinal Uses
title_fullStr Zingiber officinale var. rubrum: Red Ginger’s Medicinal Uses
title_full_unstemmed Zingiber officinale var. rubrum: Red Ginger’s Medicinal Uses
title_short Zingiber officinale var. rubrum: Red Ginger’s Medicinal Uses
title_sort zingiber officinale var. rubrum: red ginger’s medicinal uses
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840670/
https://www.ncbi.nlm.nih.gov/pubmed/35164040
http://dx.doi.org/10.3390/molecules27030775
work_keys_str_mv AT zhangshiming zingiberofficinalevarrubrumredgingersmedicinaluses
AT kouxuefang zingiberofficinalevarrubrumredgingersmedicinaluses
AT zhaohui zingiberofficinalevarrubrumredgingersmedicinaluses
AT makkitkay zingiberofficinalevarrubrumredgingersmedicinaluses
AT balijepallimadhukatyayani zingiberofficinalevarrubrumredgingersmedicinaluses
AT pichikamallikarjunarao zingiberofficinalevarrubrumredgingersmedicinaluses