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Methotrexate-loaded nanoparticles ameliorate experimental model of autoimmune arthritis by regulating the balance of interleukin-17-producing T cells and regulatory T cells

BACKGROUND: Rheumatoid arthritis (RA) is a progressive systemic autoimmune disease that is characterized by infiltration of inflammatory cells into the hyperplastic synovial tissue, resulting in subsequent destruction of adjacent articular cartilage and bone. Methotrexate (MTX), the first convention...

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Detalles Bibliográficos
Autores principales:	Park, Jin-Sil, Lee, Donghyun, Yang, SeungCheon, Jeong, Ha Yeon, Na, Hyun Sik, Cho, Keun-Hyung, Choi, JeongWon, Koo, Heebeom, Cho, Mi-La, Park, Sung-Hwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8840785/ https://www.ncbi.nlm.nih.gov/pubmed/35148758 http://dx.doi.org/10.1186/s12967-022-03267-0

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