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Facklamia hominis pyelonephritis in a pediatric patient: first case report and review of the literature

BACKGROUND: Pyelonephritis is one of the most serious bacterial illnesses during childhood. Gram-negative organisms account for up to 90% of the cases. Gram-positive bacteria are uncommon causes of urinary tract infections, and only a few cases caused by Facklamia hominis have been reported in the l...

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Autores principales: Pérez-Cavazos, Samantha, Cisneros-Saldaña, Daniela, Espinosa-Villaseñor, Fernando, Castillo-Bejarano, José Iván, Vaquera-Aparicio, Denisse Natalie, Sánchez-Alanís, Hugo, Mascareñas-De los Santos, Abiel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841125/
https://www.ncbi.nlm.nih.gov/pubmed/35151319
http://dx.doi.org/10.1186/s12941-022-00497-4
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author Pérez-Cavazos, Samantha
Cisneros-Saldaña, Daniela
Espinosa-Villaseñor, Fernando
Castillo-Bejarano, José Iván
Vaquera-Aparicio, Denisse Natalie
Sánchez-Alanís, Hugo
Mascareñas-De los Santos, Abiel
author_facet Pérez-Cavazos, Samantha
Cisneros-Saldaña, Daniela
Espinosa-Villaseñor, Fernando
Castillo-Bejarano, José Iván
Vaquera-Aparicio, Denisse Natalie
Sánchez-Alanís, Hugo
Mascareñas-De los Santos, Abiel
author_sort Pérez-Cavazos, Samantha
collection PubMed
description BACKGROUND: Pyelonephritis is one of the most serious bacterial illnesses during childhood. Gram-negative organisms account for up to 90% of the cases. Gram-positive bacteria are uncommon causes of urinary tract infections, and only a few cases caused by Facklamia hominis have been reported in the literature. CASE PRESENTATION: A five-year-old girl with tracheostomy and gastrostomy and past medical history of congenital lymphangioma presented with a two-week history of with intermittent fever, frequent urination, and vesical tenesmus. Diagnosis of pyelonephritis was made. Urine culture reported colonies with alpha-hemolysis in blood agar at 48-h of incubation and Facklamia hominis was identified by MALDI-TOF. The patient was successfully treated with gentamicin. CONCLUSIONS: This is the first reported case of pyelonephritis by Facklamia hominis in a child, and the second involving infection in a pediatric patient. Although this pathogen is uncommon, current treatment of F. hominis is a challenge for physicians. This case illustrates the requirement to standardize identification and treatment of care to avoid treatment failure and antimicrobial resistance.
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spelling pubmed-88411252022-02-16 Facklamia hominis pyelonephritis in a pediatric patient: first case report and review of the literature Pérez-Cavazos, Samantha Cisneros-Saldaña, Daniela Espinosa-Villaseñor, Fernando Castillo-Bejarano, José Iván Vaquera-Aparicio, Denisse Natalie Sánchez-Alanís, Hugo Mascareñas-De los Santos, Abiel Ann Clin Microbiol Antimicrob Case Report BACKGROUND: Pyelonephritis is one of the most serious bacterial illnesses during childhood. Gram-negative organisms account for up to 90% of the cases. Gram-positive bacteria are uncommon causes of urinary tract infections, and only a few cases caused by Facklamia hominis have been reported in the literature. CASE PRESENTATION: A five-year-old girl with tracheostomy and gastrostomy and past medical history of congenital lymphangioma presented with a two-week history of with intermittent fever, frequent urination, and vesical tenesmus. Diagnosis of pyelonephritis was made. Urine culture reported colonies with alpha-hemolysis in blood agar at 48-h of incubation and Facklamia hominis was identified by MALDI-TOF. The patient was successfully treated with gentamicin. CONCLUSIONS: This is the first reported case of pyelonephritis by Facklamia hominis in a child, and the second involving infection in a pediatric patient. Although this pathogen is uncommon, current treatment of F. hominis is a challenge for physicians. This case illustrates the requirement to standardize identification and treatment of care to avoid treatment failure and antimicrobial resistance. BioMed Central 2022-02-12 /pmc/articles/PMC8841125/ /pubmed/35151319 http://dx.doi.org/10.1186/s12941-022-00497-4 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Pérez-Cavazos, Samantha
Cisneros-Saldaña, Daniela
Espinosa-Villaseñor, Fernando
Castillo-Bejarano, José Iván
Vaquera-Aparicio, Denisse Natalie
Sánchez-Alanís, Hugo
Mascareñas-De los Santos, Abiel
Facklamia hominis pyelonephritis in a pediatric patient: first case report and review of the literature
title Facklamia hominis pyelonephritis in a pediatric patient: first case report and review of the literature
title_full Facklamia hominis pyelonephritis in a pediatric patient: first case report and review of the literature
title_fullStr Facklamia hominis pyelonephritis in a pediatric patient: first case report and review of the literature
title_full_unstemmed Facklamia hominis pyelonephritis in a pediatric patient: first case report and review of the literature
title_short Facklamia hominis pyelonephritis in a pediatric patient: first case report and review of the literature
title_sort facklamia hominis pyelonephritis in a pediatric patient: first case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841125/
https://www.ncbi.nlm.nih.gov/pubmed/35151319
http://dx.doi.org/10.1186/s12941-022-00497-4
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