The effect of the E484K mutation of SARS-CoV-2 on the neutralizing activity of antibodies from BNT162b2 vaccinated individuals

The reduced vaccine efficacy against the SARS-CoV-2 variant lineage B. 1.351 (beta variant) containing the E484K and N501Y mutations is well known. The E484K mutation in SARS-CoV-2 is thought to be responsible for weakened humoral immunity. Vaccine efficacy against the R.1 lineage, which contains th...

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Detalles Bibliográficos
Autores principales: Uwamino, Yoshifumi, Yokoyama, Takashi, Shimura, Takako, Nishimura, Tomoyasu, Sato, Yasunori, Wakui, Masatoshi, Kosaki, Kenjiro, Hasegawa, Naoki, Murata, Mitsuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841208/
https://www.ncbi.nlm.nih.gov/pubmed/35183387
http://dx.doi.org/10.1016/j.vaccine.2022.02.047

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