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Cardiac involvement in Adult Multisystemic Inflammatory Syndrome related to COVID-19. Two case reports
In this article we describe two cases that presented with persistent fever and a hyperinflammatory state in association with severe acute respiratory syndrome-coronavirus-2 infection with various negative reverse transcription-polymerase chain reaction results. These cases subsequently developed myo...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese College of Cardiology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841216/ https://www.ncbi.nlm.nih.gov/pubmed/35190758 http://dx.doi.org/10.1016/j.jccase.2022.01.017 |
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author | Carrasco-Molina, Sergio Ramos-Ruperto, Luis Ibáñez-Mendoza, Paula Martín-Gutiérrez, Juan Carlos Ruíz-Bravo, Elena Iniesta-Manjavacas, Ángel Manuel Prieto-Moriche, Elsa Robles-Marhuenda, Ángel |
author_facet | Carrasco-Molina, Sergio Ramos-Ruperto, Luis Ibáñez-Mendoza, Paula Martín-Gutiérrez, Juan Carlos Ruíz-Bravo, Elena Iniesta-Manjavacas, Ángel Manuel Prieto-Moriche, Elsa Robles-Marhuenda, Ángel |
author_sort | Carrasco-Molina, Sergio |
collection | PubMed |
description | In this article we describe two cases that presented with persistent fever and a hyperinflammatory state in association with severe acute respiratory syndrome-coronavirus-2 infection with various negative reverse transcription-polymerase chain reaction results. These cases subsequently developed myocarditis with cardiogenic shock that required vasoactive drugs and had a good response to corticosteroid treatment. All cases met criteria for a definitive case of multisystemic inflammatory syndrome in adults, a recently described entity associated with coronavirus disease 2019, which has a good response to immunomodulators and a good prognosis in most cases. <Learning objective: Multisystemic inflammatory syndrome in adults is a severe disease with predominantly cardiac involvement, associated with severe acute respiratory syndrome-coronavirus-2 infection. The presentation of these two cases shows the importance of early recognition, especially in this coronavirus 2019 pandemic scenario in which almost anyone is susceptible to have had contact with the virus. It usually has a good therapeutic response to corticosteroids and invasive diagnostic tests, such as endomyocardial biopsy, could be avoided.> |
format | Online Article Text |
id | pubmed-8841216 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Japanese College of Cardiology |
record_format | MEDLINE/PubMed |
spelling | pubmed-88412162022-02-14 Cardiac involvement in Adult Multisystemic Inflammatory Syndrome related to COVID-19. Two case reports Carrasco-Molina, Sergio Ramos-Ruperto, Luis Ibáñez-Mendoza, Paula Martín-Gutiérrez, Juan Carlos Ruíz-Bravo, Elena Iniesta-Manjavacas, Ángel Manuel Prieto-Moriche, Elsa Robles-Marhuenda, Ángel J Cardiol Cases Case Report In this article we describe two cases that presented with persistent fever and a hyperinflammatory state in association with severe acute respiratory syndrome-coronavirus-2 infection with various negative reverse transcription-polymerase chain reaction results. These cases subsequently developed myocarditis with cardiogenic shock that required vasoactive drugs and had a good response to corticosteroid treatment. All cases met criteria for a definitive case of multisystemic inflammatory syndrome in adults, a recently described entity associated with coronavirus disease 2019, which has a good response to immunomodulators and a good prognosis in most cases. <Learning objective: Multisystemic inflammatory syndrome in adults is a severe disease with predominantly cardiac involvement, associated with severe acute respiratory syndrome-coronavirus-2 infection. The presentation of these two cases shows the importance of early recognition, especially in this coronavirus 2019 pandemic scenario in which almost anyone is susceptible to have had contact with the virus. It usually has a good therapeutic response to corticosteroids and invasive diagnostic tests, such as endomyocardial biopsy, could be avoided.> Japanese College of Cardiology 2022-02-14 /pmc/articles/PMC8841216/ /pubmed/35190758 http://dx.doi.org/10.1016/j.jccase.2022.01.017 Text en © 2022 Japanese College of Cardiology. Published by Elsevier Ltd. All rights reserved. |
spellingShingle | Case Report Carrasco-Molina, Sergio Ramos-Ruperto, Luis Ibáñez-Mendoza, Paula Martín-Gutiérrez, Juan Carlos Ruíz-Bravo, Elena Iniesta-Manjavacas, Ángel Manuel Prieto-Moriche, Elsa Robles-Marhuenda, Ángel Cardiac involvement in Adult Multisystemic Inflammatory Syndrome related to COVID-19. Two case reports |
title | Cardiac involvement in Adult Multisystemic Inflammatory Syndrome related to COVID-19. Two case reports |
title_full | Cardiac involvement in Adult Multisystemic Inflammatory Syndrome related to COVID-19. Two case reports |
title_fullStr | Cardiac involvement in Adult Multisystemic Inflammatory Syndrome related to COVID-19. Two case reports |
title_full_unstemmed | Cardiac involvement in Adult Multisystemic Inflammatory Syndrome related to COVID-19. Two case reports |
title_short | Cardiac involvement in Adult Multisystemic Inflammatory Syndrome related to COVID-19. Two case reports |
title_sort | cardiac involvement in adult multisystemic inflammatory syndrome related to covid-19. two case reports |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841216/ https://www.ncbi.nlm.nih.gov/pubmed/35190758 http://dx.doi.org/10.1016/j.jccase.2022.01.017 |
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