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Effect of axitinib regulating the pathological blood–brain barrier functional recovery for glioblastoma therapeutics

AIMS: Dysfunction of the blood–brain barrier (BBB) is a prominent pathological feature of glioblastoma (GBM). Vascular endothelial growth factor (VEGF) is confirmed to be abnormally elevated in the pathogenesis of GBM, causing BBB pathological disruption, which further allows the leakage of neurotox...

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Detalles Bibliográficos
Autores principales: Zhang, Fengtian, Wen, Lijuan, Wang, Kai, Huang, Zhihua, Jin, Xiangyu, Xiong, Ruiwen, He, Shiying, Hu, Fuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841308/
https://www.ncbi.nlm.nih.gov/pubmed/34967104
http://dx.doi.org/10.1111/cns.13788