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Effect of axitinib regulating the pathological blood–brain barrier functional recovery for glioblastoma therapeutics
AIMS: Dysfunction of the blood–brain barrier (BBB) is a prominent pathological feature of glioblastoma (GBM). Vascular endothelial growth factor (VEGF) is confirmed to be abnormally elevated in the pathogenesis of GBM, causing BBB pathological disruption, which further allows the leakage of neurotox...
Autores principales: | Zhang, Fengtian, Wen, Lijuan, Wang, Kai, Huang, Zhihua, Jin, Xiangyu, Xiong, Ruiwen, He, Shiying, Hu, Fuqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841308/ https://www.ncbi.nlm.nih.gov/pubmed/34967104 http://dx.doi.org/10.1111/cns.13788 |
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