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Preclinical Pharmacokinetics and Dosimetry of an (89)Zr Labelled Anti-PDL1 in an Orthotopic Lung Cancer Murine Model

Anti-PDL1 is a monoclonal antibody targeting the programmed death-cell ligand (PD-L1) by blocking the programmed death-cell (PD-1)/PD-L1 axis. It restores the immune system response in several tumours, such as non-small cell lung cancer (NSCLC). Anti-PDL1 or anti-PD1 treatments rely on PD-L1 tumoura...

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Detalles Bibliográficos
Autores principales:	Krache, Anis, Fontan, Charlotte, Pestourie, Carine, Bardiès, Manuel, Bouvet, Yann, Payoux, Pierre, Chatelut, Etienne, White-Koning, Melanie, Salabert, Anne-Sophie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841431/ https://www.ncbi.nlm.nih.gov/pubmed/35174180 http://dx.doi.org/10.3389/fmed.2021.741855

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