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Pharmacogenomics of celiprolol – evidence for a role of P‐glycoprotein and organic anion transporting polypeptide 1A2 in celiprolol pharmacokinetics

The aim of this study was to search for associations of genetic variants with celiprolol pharmacokinetics in a large set of pharmacokinetic genes, and, more specifically, in a set of previously identified candidate genes ABCB1, SLCO1A2, and SLCO2B1. To this end, we determined celiprolol single‐dose...

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Detalles Bibliográficos
Autores principales: Hirvensalo, Päivi, Tornio, Aleksi, Tapaninen, Tuija, Paile‐Hyvärinen, Maria, Neuvonen, Mikko, Backman, Janne T., Niemi, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841435/
https://www.ncbi.nlm.nih.gov/pubmed/34585840
http://dx.doi.org/10.1111/cts.13159