The Effects of Acute and Chronic Selective Phosphodiesterase 1 Inhibition on Smooth Muscle Cell-Associated Aging Features

Age-related cardiovascular diseases (CVDs) remain among the leading global causes of death, and vascular smooth muscle cell (VSMC) remodeling plays an essential role in its pathology. Reduced NO-cGMP pathway signaling is a major feature and pathogenic mechanism underlying vasodilator dysfunction. Re...

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Detalles Bibliográficos
Autores principales: Golshiri, Keivan, Ataabadi, Ehsan Ataei, Jüttner, Annika A., Snyder, Gretchen L., Davis, Robert E, Lin, Amy, Zhang, Lei, de Vries, René, Garrelds, Ingrid M, Leijten, Frank P. J., Danser, A. H. Jan, Roks, Anton J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841451/
https://www.ncbi.nlm.nih.gov/pubmed/35173613
http://dx.doi.org/10.3389/fphar.2021.818355

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