A phase I study to evaluate the safety, tolerability, pharmacodynamic and pharmacokinetic profiles of ocular GLH8NDE in healthy male adults

GLH8NDE, a derivative of eupatilin, is currently under development to treat dry eye disease. We conducted a randomized, double‐masked, placebo‐controlled, single‐ and multiple‐day study to evaluate safety, tolerability, pharmacodynamics, and pharmacokinetics of ocular GLH8NDE in healthy male adults....

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Detalles Bibliográficos
Autores principales: Jung, Jihyun, Huh, Ki Young, Jin, Xuanyou, Ha, Ahnul, Park, Ki Ho, Park, Jun Sang, Kim, Eunjung, Lee, Jaehwi, Jang, In‐Jin, Lee, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841454/
https://www.ncbi.nlm.nih.gov/pubmed/34523814
http://dx.doi.org/10.1111/cts.13150

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