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Evaluation of the abuse potential of difelikefalin, a selective kappa‐opioid receptor agonist, in recreational polydrug users
Difelikefalin, a selective kappa‐opioid receptor agonist with limited central nervous system penetration, is being developed for the treatment of chronic pruritic conditions. This randomized, double‐blind, active‐ and placebo‐controlled, four‐way crossover study was designed to evaluate the abuse po...
Autores principales: | Shram, Megan J., Spencer, Robert H., Qian, Jenny, Munera, Catherine L., Lewis, Michael E., Henningfield, Jack E., Webster, Lynn, Menzaghi, Frédérique |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841457/ https://www.ncbi.nlm.nih.gov/pubmed/34708917 http://dx.doi.org/10.1111/cts.13173 |
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