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Adapting regulatory drug‐drug interaction guidance to design clinical pharmacokinetic natural product‐drug interaction studies: A NaPDI Center recommended approach

Pharmacokinetic drug interactions precipitated by botanical and other natural products (NPs) remain critically understudied. Investigating these complex interactions is fraught with difficulties due to the methodologic and technical challenges associated with the inherently complex chemistries and p...

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Detalles Bibliográficos
Autores principales:	Cox, Emily J., Rettie, Allan E., Unadkat, Jashvant D., Thummel, Kenneth E., McCune, Jeannine S., Paine, Mary F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841492/ https://www.ncbi.nlm.nih.gov/pubmed/34699676 http://dx.doi.org/10.1111/cts.13172

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