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Targeting Tryptophan Catabolism in Cancer Immunotherapy Era: Challenges and Perspectives

Metabolism of tryptophan (Trp), an essential amino acid, represent a major metabolic pathway that both promotes tumor cell intrinsic malignant properties as well as restricts antitumour immunity, thus emerging as a drug development target for cancer immunotherapy. Three cytosolic enzymes, namely ind...

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Detalles Bibliográficos
Autores principales:	Peyraud, Florent, Guegan, Jean-Philippe, Bodet, Dominique, Cousin, Sophie, Bessede, Alban, Italiano, Antoine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841724/ https://www.ncbi.nlm.nih.gov/pubmed/35173722 http://dx.doi.org/10.3389/fimmu.2022.807271

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