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CRISPR Cas13-Based Tools to Track and Manipulate Endogenous Telomeric Repeat-Containing RNAs in Live Cells

TERRA, TElomeric Repeat-containing RNA, is a long non-coding RNA transcribed from telomeres. Emerging evidence indicates that TERRA regulates telomere maintenance and chromosome end protection in normal and cancerous cells. However, the mechanism of how TERRA contributes to telomere functions is sti...

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Detalles Bibliográficos
Autores principales:	Xu, Meng, Chigumira, Tafadzwa, Chen, Ziheng, Tones, Jason, Zhao, Rongwei, Dahl, Kris Noel, Chenoweth, David M., Zhang, Huaiying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841788/ https://www.ncbi.nlm.nih.gov/pubmed/35174207 http://dx.doi.org/10.3389/fmolb.2021.785160

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