Therapeutic effects of TM4SF5-targeting chimeric and humanized monoclonal antibodies in hepatocellular and colon cancer models

The transmembrane 4 L six family member 5 (TM4SF5) is aberrantly expressed in hepatocellular and colorectal cancers, and has been implicated in tumor progression, suggesting that it could serve as a novel therapeutic target. Previously, we screened a murine antibody phage-display library to generate...

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Detalles Bibliográficos
Autores principales: Ko, Dongjoon, Kim, Eunmi, Shin, Eun-Ae, Nam, Seo Hee, Yoon, Junghwa, Lee, Jin-Sook, Lee, Yunhee, Park, Sora, Ha, Kyungsoo, Choi, So-Young, Lee, Jung Weon, Kim, Semi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841960/
https://www.ncbi.nlm.nih.gov/pubmed/35211652
http://dx.doi.org/10.1016/j.omto.2022.01.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841960/
https://www.ncbi.nlm.nih.gov/pubmed/35211652
http://dx.doi.org/10.1016/j.omto.2022.01.006

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