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TMAO-Activated Hepatocyte-Derived Exosomes Impair Angiogenesis via Repressing CXCR4

Objective: Trimethylamine-N-oxide (TMAO) was found to play crucial roles in vascular endothelial function. However, the exact molecular mechanisms are not yet entirely clear. Recently, we found that exosomes (Exos) isolated from TMAO-treated hepatocytes (TMAO-Exos) contained a distinctive profile of...

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Detalles Bibliográficos
Autores principales:	Liu, Xiang, Shao, Yijia, Tu, Jiazichao, Sun, Jiapan, Dong, Bing, Wang, Zhichao, Zhou, Jianrong, Chen, Long, Tao, Jun, Chen, Jimei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8841965/ https://www.ncbi.nlm.nih.gov/pubmed/35174166 http://dx.doi.org/10.3389/fcell.2021.804049

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