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Relationship between Vertebral Instability and the Cross-Sectional Area of Lumbar Muscles in Postmenopausal Acute Osteoporotic Vertebral Fractures
INTRODUCTION: Vertebral instability (VI) in osteoporotic vertebral fractures (OVFs) varies from mild to severe. The relationship between the VI of OVFs and independent factors, such as bone mineral density (BMD) and lumbar muscle volume, is unclear. This study aimed to investigate whether BMD and th...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society for Spine Surgery and Related Research
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842355/ https://www.ncbi.nlm.nih.gov/pubmed/35224247 http://dx.doi.org/10.22603/ssrr.2021-0029 |
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author | Okuwaki, Shun Funayama, Toru Ikumi, Akira Matsuura, Satoshi Kawamura, Haruo Yamazaki, Masashi |
author_facet | Okuwaki, Shun Funayama, Toru Ikumi, Akira Matsuura, Satoshi Kawamura, Haruo Yamazaki, Masashi |
author_sort | Okuwaki, Shun |
collection | PubMed |
description | INTRODUCTION: Vertebral instability (VI) in osteoporotic vertebral fractures (OVFs) varies from mild to severe. The relationship between the VI of OVFs and independent factors, such as bone mineral density (BMD) and lumbar muscle volume, is unclear. This study aimed to investigate whether BMD and the cross-sectional area (CSA) of lumbar muscles are related to VI in OVFs. METHODS: On the basis of the thoracolumbar lateral radiographs of 95 acute OVFs in postmenopausal women (mean age 80.6 years; range: 64-103 years), supine and standing vertebral collapse rates (CRsp and CRst, respectively) were determined. Subsequently, VI was defined as follows: VI=CRst−CRsp. Using axial T2-weighted magnetic resonance imaging (MRI), CSA of the psoas major, erector spinae, and multifidus muscles at the L3/4 intervertebral disc level were measured. The BMD of the lumbar spine and proximal femur (total hip) was measured for all participants using dual-energy X-ray absorptiometry. The patients were classified into group 1 (VI <20%) and group 2 (VI ≥20%). RESULTS: We observed a negative correlation between VI and CSA of the erector spinae muscle (r=−0.3962, P<0.0001). No significant correlations were observed between VI and BMD. The CSA of the erector spinae muscle in group 2 was significantly lower than that in group 1 (P=0.0002). No significant difference in the BMD or the CSA of the psoas major or multifidus muscles was observed between the two groups. A multivariable analysis of factors of VI was performed. Both age (odds ratio [OR], 1.099; 95% confidence interval [CI], 1.015-1.189; P=0.020) and the CSA of the erector spinae (OR, 0.996; 95% CI, 0.993-0.999; P=0.020) were significant predictors of high VI. CONCLUSIONS: Although the severity of OVFs was related to the CSA of the erector spinae muscle, it was not associated with BMD. |
format | Online Article Text |
id | pubmed-8842355 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Japanese Society for Spine Surgery and Related Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-88423552022-02-25 Relationship between Vertebral Instability and the Cross-Sectional Area of Lumbar Muscles in Postmenopausal Acute Osteoporotic Vertebral Fractures Okuwaki, Shun Funayama, Toru Ikumi, Akira Matsuura, Satoshi Kawamura, Haruo Yamazaki, Masashi Spine Surg Relat Res Original Article INTRODUCTION: Vertebral instability (VI) in osteoporotic vertebral fractures (OVFs) varies from mild to severe. The relationship between the VI of OVFs and independent factors, such as bone mineral density (BMD) and lumbar muscle volume, is unclear. This study aimed to investigate whether BMD and the cross-sectional area (CSA) of lumbar muscles are related to VI in OVFs. METHODS: On the basis of the thoracolumbar lateral radiographs of 95 acute OVFs in postmenopausal women (mean age 80.6 years; range: 64-103 years), supine and standing vertebral collapse rates (CRsp and CRst, respectively) were determined. Subsequently, VI was defined as follows: VI=CRst−CRsp. Using axial T2-weighted magnetic resonance imaging (MRI), CSA of the psoas major, erector spinae, and multifidus muscles at the L3/4 intervertebral disc level were measured. The BMD of the lumbar spine and proximal femur (total hip) was measured for all participants using dual-energy X-ray absorptiometry. The patients were classified into group 1 (VI <20%) and group 2 (VI ≥20%). RESULTS: We observed a negative correlation between VI and CSA of the erector spinae muscle (r=−0.3962, P<0.0001). No significant correlations were observed between VI and BMD. The CSA of the erector spinae muscle in group 2 was significantly lower than that in group 1 (P=0.0002). No significant difference in the BMD or the CSA of the psoas major or multifidus muscles was observed between the two groups. A multivariable analysis of factors of VI was performed. Both age (odds ratio [OR], 1.099; 95% confidence interval [CI], 1.015-1.189; P=0.020) and the CSA of the erector spinae (OR, 0.996; 95% CI, 0.993-0.999; P=0.020) were significant predictors of high VI. CONCLUSIONS: Although the severity of OVFs was related to the CSA of the erector spinae muscle, it was not associated with BMD. The Japanese Society for Spine Surgery and Related Research 2021-06-11 /pmc/articles/PMC8842355/ /pubmed/35224247 http://dx.doi.org/10.22603/ssrr.2021-0029 Text en Copyright © 2022 by The Japanese Society for Spine Surgery and Related Research https://creativecommons.org/licenses/by-nc-nd/4.0/Spine Surgery and Related Research is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Original Article Okuwaki, Shun Funayama, Toru Ikumi, Akira Matsuura, Satoshi Kawamura, Haruo Yamazaki, Masashi Relationship between Vertebral Instability and the Cross-Sectional Area of Lumbar Muscles in Postmenopausal Acute Osteoporotic Vertebral Fractures |
title | Relationship between Vertebral Instability and the Cross-Sectional Area of Lumbar Muscles in Postmenopausal Acute Osteoporotic Vertebral Fractures |
title_full | Relationship between Vertebral Instability and the Cross-Sectional Area of Lumbar Muscles in Postmenopausal Acute Osteoporotic Vertebral Fractures |
title_fullStr | Relationship between Vertebral Instability and the Cross-Sectional Area of Lumbar Muscles in Postmenopausal Acute Osteoporotic Vertebral Fractures |
title_full_unstemmed | Relationship between Vertebral Instability and the Cross-Sectional Area of Lumbar Muscles in Postmenopausal Acute Osteoporotic Vertebral Fractures |
title_short | Relationship between Vertebral Instability and the Cross-Sectional Area of Lumbar Muscles in Postmenopausal Acute Osteoporotic Vertebral Fractures |
title_sort | relationship between vertebral instability and the cross-sectional area of lumbar muscles in postmenopausal acute osteoporotic vertebral fractures |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842355/ https://www.ncbi.nlm.nih.gov/pubmed/35224247 http://dx.doi.org/10.22603/ssrr.2021-0029 |
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