Cargando…
Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms
Due to their similarities in anatomy, physiology, and pharmacology to humans, mice are a valuable model system to study the generation and mechanisms modulating conventional outflow resistance and thus intraocular pressure. In addition, mouse models are critical for understanding the complex nature...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842499/ https://www.ncbi.nlm.nih.gov/pubmed/35129590 http://dx.doi.org/10.1167/iovs.63.2.12 |
| _version_ | 1784651061621948416 |
|---|---|
| author | McDowell, Colleen M. Kizhatil, Krishnakumar Elliott, Michael H. Overby, Darryl R. van Batenburg-Sherwood, Joseph Millar, J. Cameron Kuehn, Markus H. Zode, Gulab Acott, Ted S. Anderson, Michael G. Bhattacharya, Sanjoy K. Bertrand, Jacques A. Borras, Terete Bovenkamp, Diane E. Cheng, Lin Danias, John De Ieso, Michael Lucio Du, Yiqin Faralli, Jennifer A. Fuchshofer, Rudolf Ganapathy, Preethi S. Gong, Haiyan Herberg, Samuel Hernandez, Humberto Humphries, Peter John, Simon W. M. Kaufman, Paul L. Keller, Kate E. Kelley, Mary J. Kelly, Ruth A. Krizaj, David Kumar, Ajay Leonard, Brian C. Lieberman, Raquel L. Liton, Paloma Liu, Yutao Liu, Katy C. Lopez, Navita N. Mao, Weiming Mavlyutov, Timur McDonnell, Fiona McLellan, Gillian J. Mzyk, Philip Nartey, Andrews Pasquale, Louis R. Patel, Gaurang C. Pattabiraman, Padmanabhan P. Peters, Donna M. Raghunathan, Vijaykrishna Rao, Ponugoti Vasantha Rayana, Naga Raychaudhuri, Urmimala Reina-Torres, Ester Ren, Ruiyi Rhee, Douglas Chowdhury, Uttio Roy Samples, John R. Samples, E. Griffen Sharif, Najam Schuman, Joel S. Sheffield, Val C. Stevenson, Cooper H. Soundararajan, Avinash Subramanian, Preeti Sugali, Chenna Kesavulu Sun, Yang Toris, Carol B. Torrejon, Karen Y. Vahabikashi, Amir Vranka, Janice A. Wang, Ting Willoughby, Colin E. Xin, Chen Yun, Hongmin Zhang, Hao F. Fautsch, Michael P. Tamm, Ernst R. Clark, Abbot F. Ethier, C. Ross Stamer, W. Daniel |
| author_facet | McDowell, Colleen M. Kizhatil, Krishnakumar Elliott, Michael H. Overby, Darryl R. van Batenburg-Sherwood, Joseph Millar, J. Cameron Kuehn, Markus H. Zode, Gulab Acott, Ted S. Anderson, Michael G. Bhattacharya, Sanjoy K. Bertrand, Jacques A. Borras, Terete Bovenkamp, Diane E. Cheng, Lin Danias, John De Ieso, Michael Lucio Du, Yiqin Faralli, Jennifer A. Fuchshofer, Rudolf Ganapathy, Preethi S. Gong, Haiyan Herberg, Samuel Hernandez, Humberto Humphries, Peter John, Simon W. M. Kaufman, Paul L. Keller, Kate E. Kelley, Mary J. Kelly, Ruth A. Krizaj, David Kumar, Ajay Leonard, Brian C. Lieberman, Raquel L. Liton, Paloma Liu, Yutao Liu, Katy C. Lopez, Navita N. Mao, Weiming Mavlyutov, Timur McDonnell, Fiona McLellan, Gillian J. Mzyk, Philip Nartey, Andrews Pasquale, Louis R. Patel, Gaurang C. Pattabiraman, Padmanabhan P. Peters, Donna M. Raghunathan, Vijaykrishna Rao, Ponugoti Vasantha Rayana, Naga Raychaudhuri, Urmimala Reina-Torres, Ester Ren, Ruiyi Rhee, Douglas Chowdhury, Uttio Roy Samples, John R. Samples, E. Griffen Sharif, Najam Schuman, Joel S. Sheffield, Val C. Stevenson, Cooper H. Soundararajan, Avinash Subramanian, Preeti Sugali, Chenna Kesavulu Sun, Yang Toris, Carol B. Torrejon, Karen Y. Vahabikashi, Amir Vranka, Janice A. Wang, Ting Willoughby, Colin E. Xin, Chen Yun, Hongmin Zhang, Hao F. Fautsch, Michael P. Tamm, Ernst R. Clark, Abbot F. Ethier, C. Ross Stamer, W. Daniel |
| author_sort | McDowell, Colleen M. |
| collection | PubMed |
| description | Due to their similarities in anatomy, physiology, and pharmacology to humans, mice are a valuable model system to study the generation and mechanisms modulating conventional outflow resistance and thus intraocular pressure. In addition, mouse models are critical for understanding the complex nature of conventional outflow homeostasis and dysfunction that results in ocular hypertension. In this review, we describe a set of minimum acceptable standards for developing, characterizing, and utilizing mouse models of open-angle ocular hypertension. We expect that this set of standard practices will increase scientific rigor when using mouse models and will better enable researchers to replicate and build upon previous findings. |
| format | Online Article Text |
| id | pubmed-8842499 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2022 |
| publisher | The Association for Research in Vision and Ophthalmology |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-88424992022-02-18 Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms McDowell, Colleen M. Kizhatil, Krishnakumar Elliott, Michael H. Overby, Darryl R. van Batenburg-Sherwood, Joseph Millar, J. Cameron Kuehn, Markus H. Zode, Gulab Acott, Ted S. Anderson, Michael G. Bhattacharya, Sanjoy K. Bertrand, Jacques A. Borras, Terete Bovenkamp, Diane E. Cheng, Lin Danias, John De Ieso, Michael Lucio Du, Yiqin Faralli, Jennifer A. Fuchshofer, Rudolf Ganapathy, Preethi S. Gong, Haiyan Herberg, Samuel Hernandez, Humberto Humphries, Peter John, Simon W. M. Kaufman, Paul L. Keller, Kate E. Kelley, Mary J. Kelly, Ruth A. Krizaj, David Kumar, Ajay Leonard, Brian C. Lieberman, Raquel L. Liton, Paloma Liu, Yutao Liu, Katy C. Lopez, Navita N. Mao, Weiming Mavlyutov, Timur McDonnell, Fiona McLellan, Gillian J. Mzyk, Philip Nartey, Andrews Pasquale, Louis R. Patel, Gaurang C. Pattabiraman, Padmanabhan P. Peters, Donna M. Raghunathan, Vijaykrishna Rao, Ponugoti Vasantha Rayana, Naga Raychaudhuri, Urmimala Reina-Torres, Ester Ren, Ruiyi Rhee, Douglas Chowdhury, Uttio Roy Samples, John R. Samples, E. Griffen Sharif, Najam Schuman, Joel S. Sheffield, Val C. Stevenson, Cooper H. Soundararajan, Avinash Subramanian, Preeti Sugali, Chenna Kesavulu Sun, Yang Toris, Carol B. Torrejon, Karen Y. Vahabikashi, Amir Vranka, Janice A. Wang, Ting Willoughby, Colin E. Xin, Chen Yun, Hongmin Zhang, Hao F. Fautsch, Michael P. Tamm, Ernst R. Clark, Abbot F. Ethier, C. Ross Stamer, W. Daniel Invest Ophthalmol Vis Sci Perspective Due to their similarities in anatomy, physiology, and pharmacology to humans, mice are a valuable model system to study the generation and mechanisms modulating conventional outflow resistance and thus intraocular pressure. In addition, mouse models are critical for understanding the complex nature of conventional outflow homeostasis and dysfunction that results in ocular hypertension. In this review, we describe a set of minimum acceptable standards for developing, characterizing, and utilizing mouse models of open-angle ocular hypertension. We expect that this set of standard practices will increase scientific rigor when using mouse models and will better enable researchers to replicate and build upon previous findings. The Association for Research in Vision and Ophthalmology 2022-02-07 /pmc/articles/PMC8842499/ /pubmed/35129590 http://dx.doi.org/10.1167/iovs.63.2.12 Text en Copyright 2022 The Authors https://creativecommons.org/licenses/by/4.0/This work is licensed under a Creative Commons Attribution 4.0 International License. |
| spellingShingle | Perspective McDowell, Colleen M. Kizhatil, Krishnakumar Elliott, Michael H. Overby, Darryl R. van Batenburg-Sherwood, Joseph Millar, J. Cameron Kuehn, Markus H. Zode, Gulab Acott, Ted S. Anderson, Michael G. Bhattacharya, Sanjoy K. Bertrand, Jacques A. Borras, Terete Bovenkamp, Diane E. Cheng, Lin Danias, John De Ieso, Michael Lucio Du, Yiqin Faralli, Jennifer A. Fuchshofer, Rudolf Ganapathy, Preethi S. Gong, Haiyan Herberg, Samuel Hernandez, Humberto Humphries, Peter John, Simon W. M. Kaufman, Paul L. Keller, Kate E. Kelley, Mary J. Kelly, Ruth A. Krizaj, David Kumar, Ajay Leonard, Brian C. Lieberman, Raquel L. Liton, Paloma Liu, Yutao Liu, Katy C. Lopez, Navita N. Mao, Weiming Mavlyutov, Timur McDonnell, Fiona McLellan, Gillian J. Mzyk, Philip Nartey, Andrews Pasquale, Louis R. Patel, Gaurang C. Pattabiraman, Padmanabhan P. Peters, Donna M. Raghunathan, Vijaykrishna Rao, Ponugoti Vasantha Rayana, Naga Raychaudhuri, Urmimala Reina-Torres, Ester Ren, Ruiyi Rhee, Douglas Chowdhury, Uttio Roy Samples, John R. Samples, E. Griffen Sharif, Najam Schuman, Joel S. Sheffield, Val C. Stevenson, Cooper H. Soundararajan, Avinash Subramanian, Preeti Sugali, Chenna Kesavulu Sun, Yang Toris, Carol B. Torrejon, Karen Y. Vahabikashi, Amir Vranka, Janice A. Wang, Ting Willoughby, Colin E. Xin, Chen Yun, Hongmin Zhang, Hao F. Fautsch, Michael P. Tamm, Ernst R. Clark, Abbot F. Ethier, C. Ross Stamer, W. Daniel Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms |
| title | Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms |
| title_full | Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms |
| title_fullStr | Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms |
| title_full_unstemmed | Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms |
| title_short | Consensus Recommendation for Mouse Models of Ocular Hypertension to Study Aqueous Humor Outflow and Its Mechanisms |
| title_sort | consensus recommendation for mouse models of ocular hypertension to study aqueous humor outflow and its mechanisms |
| topic | Perspective |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842499/ https://www.ncbi.nlm.nih.gov/pubmed/35129590 http://dx.doi.org/10.1167/iovs.63.2.12 |
| work_keys_str_mv | AT mcdowellcolleenm consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT kizhatilkrishnakumar consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT elliottmichaelh consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT overbydarrylr consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT vanbatenburgsherwoodjoseph consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT millarjcameron consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT kuehnmarkush consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT zodegulab consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT acottteds consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT andersonmichaelg consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT bhattacharyasanjoyk consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT bertrandjacquesa consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT borrasterete consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT bovenkampdianee consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT chenglin consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT daniasjohn consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT deiesomichaellucio consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT duyiqin consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT farallijennifera consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT fuchshoferrudolf consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT ganapathypreethis consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT gonghaiyan consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT herbergsamuel consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT hernandezhumberto consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT humphriespeter consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT johnsimonwm consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT kaufmanpaull consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT kellerkatee consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT kelleymaryj consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT kellyrutha consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT krizajdavid consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT kumarajay consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT leonardbrianc consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT liebermanraquell consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT litonpaloma consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT liuyutao consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT liukatyc consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT lopeznavitan consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT maoweiming consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT mavlyutovtimur consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT mcdonnellfiona consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT mclellangillianj consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT mzykphilip consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT narteyandrews consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT pasqualelouisr consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT patelgaurangc consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT pattabiramanpadmanabhanp consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT petersdonnam consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT raghunathanvijaykrishna consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT raoponugotivasantha consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT rayananaga consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT raychaudhuriurmimala consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT reinatorresester consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT renruiyi consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT rheedouglas consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT chowdhuryuttioroy consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT samplesjohnr consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT samplesegriffen consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT sharifnajam consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT schumanjoels consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT sheffieldvalc consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT stevensoncooperh consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT soundararajanavinash consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT subramanianpreeti consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT sugalichennakesavulu consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT sunyang consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT toriscarolb consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT torrejonkareny consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT vahabikashiamir consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT vrankajanicea consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT wangting consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT willoughbycoline consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT xinchen consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT yunhongmin consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT zhanghaof consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT fautschmichaelp consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT tammernstr consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT clarkabbotf consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT ethiercross consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms AT stamerwdaniel consensusrecommendationformousemodelsofocularhypertensiontostudyaqueoushumoroutflowanditsmechanisms |