Novel Derivatives of diphenyl-1,3,4-oxadiazol as Ligands of Benzodiazepine Receptors; Synthesize, Binding Assay and Pharmacological Evaluation

Benzodiazepines (BZD) are among the main classes of tranquilizing drugs, bearing much less toxicity compared to other drugs acting on the CNS. Considering the pharmacophore model of BZD binding to GABA-A receptor, novel diphenyl 1,3,4-oxadiazole compounds as BZD ligands were designed. The compounds...

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Detalles Bibliográficos
Autores principales: Khoramjouy, Mona, Zarepishe, Naeime, Rezaee, Elham, Imani, Ali, Mahmoudzadeh-mandolakani, Rojin, Hashemi, Seyedali, Fallah, Moones, Hasheminasab, Golnar, Shahhosseini, Soraya, Tabatabai, Sayyed Abbas, Faizi, Mehrdad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842605/
https://www.ncbi.nlm.nih.gov/pubmed/35194427
http://dx.doi.org/10.22037/ijpr.2021.115549.15429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842605/
https://www.ncbi.nlm.nih.gov/pubmed/35194427
http://dx.doi.org/10.22037/ijpr.2021.115549.15429

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