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Site-Specific Cerebrospinal Fluid Tau Hyperphosphorylation in Response to Alzheimer’s Disease Brain Pathology: Not All Tau Phospho-Sites are Hyperphosphorylated

BACKGROUND: Understanding patterns of association between CSF phosphorylated tau (p-tau) species and clinical disease severity will aid Alzheimer’s disease (AD) diagnosis and treatment. OBJECTIVE: To evaluate changes in tau phosphorylation ratios to brain imaging (amyloid PET, [(18)F]GTP1 PET, and M...

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Detalles Bibliográficos
Autores principales:	Barthélemy, Nicolas R., Toth, Balazs, Manser, Paul T., Sanabria-Bohórquez, Sandra, Teng, Edmond, Keeley, Michael, Bateman, Randall J., Weimer, Robby M., Wildsmith, Kristin R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842784/ https://www.ncbi.nlm.nih.gov/pubmed/34806603 http://dx.doi.org/10.3233/JAD-210677

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