Microtubule disruption reduces metastasis more effectively than primary tumor growth

Clinical cancer imaging focuses on tumor growth rather than metastatic phenotypes. The microtubule-depolymerizing drug, Vinorelbine, reduced the metastatic phenotypes of microtentacles, reattachment and tumor cell clustering more than tumor cell viability. Treating mice with Vinorelbine for only 24 ...

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Detalles Bibliográficos
Autores principales: Thompson, Keyata N., Ju, Julia A., Ory, Eleanor C., Pratt, Stephen J. P., Lee, Rachel M., Mathias, Trevor J., Chang, Katarina T., Lee, Cornell J., Goloubeva, Olga G., Bailey, Patrick C., Chakrabarti, Kristi R., Jewell, Christopher M., Vitolo, Michele I., Martin, Stuart S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842877/
https://www.ncbi.nlm.nih.gov/pubmed/35164808
http://dx.doi.org/10.1186/s13058-022-01506-2

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