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Tumor necrosis factor alpha neutralization attenuates immune checkpoint inhibitor-induced activation of intermediate monocytes in synovial fluid mononuclear cells from patients with inflammatory arthritis

OBJECTIVE: During treatment with immune checkpoint inhibitors (ICI) such as the anti-PD-1 antibody pembrolizumab, half of patients with pre-existing inflammatory arthritis experience disease flares. The underlying immunological mechanisms have not been characterized. Here, we investigate the effect...

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Detalles Bibliográficos
Autores principales:	Sørensen, Anne Sofie, Andersen, Morten Nørgaard, Juul-Madsen, Kristian, Broksø, Amalie Dyrelund, Skejø, Cæcilie, Schmidt, Henrik, Vorup-Jensen, Thomas, Kragstrup, Tue Wenzel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8842914/ https://www.ncbi.nlm.nih.gov/pubmed/35164829 http://dx.doi.org/10.1186/s13075-022-02737-6

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