Cargando…
HP05: Diagnostic and prognostic assessment in respiratory and hemodynamic changes related to prone position in COVID-19 patients
Objective: One of the most relevant findings of COVID-19 is the respiratory damage that leads to an impairment in tissue oxygenation during the course of the disease. To study this disease's physiopathology, we have analyzed the respiratory patterns and the hemodynamic variations related to pos...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Published by Elsevier B.V.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843056/ http://dx.doi.org/10.1016/j.clinph.2021.11.012 |
_version_ | 1784651171422535680 |
---|---|
author | López-Viñas, L. Roy-Vallejo, E. Rocío-Martín, E. De La Rosa Santiago, E. Zamora-García, E. Galván-Román, J.M. Wix-Ramos, R. |
author_facet | López-Viñas, L. Roy-Vallejo, E. Rocío-Martín, E. De La Rosa Santiago, E. Zamora-García, E. Galván-Román, J.M. Wix-Ramos, R. |
author_sort | López-Viñas, L. |
collection | PubMed |
description | Objective: One of the most relevant findings of COVID-19 is the respiratory damage that leads to an impairment in tissue oxygenation during the course of the disease. To study this disease's physiopathology, we have analyzed the respiratory patterns and the hemodynamic variations related to postural changes in inpatients with COVID-19. Methods: We performed a prospective study including 11 polygraph and hemodynamic studies from inpatients admitted for COVID-19 who benefited from positional changes. To assess the respiratory parameters, we conducted polygraph studies. To evaluate the hemodynamic variables, we used a thoracic electrical bioimpedance. Results: We observed a minimum oxygen saturation median of 85.00% (IQR: 7.00) in the supine position vs 91.00% (IQR: 8.00) in the prone position (p=0.173). The airflow restriction in the supine position was 2.70% (IQR: 6.55) vs 1.55% (IQR: 2.80) in the prone position (p=0.383). We observed a slight tendency to decrease in all parameters in the prone position concerning the hemodynamic variables, although they were no statistically significant. We show a decrease in vascular resistance mean in the prone position, being 18.2% vs 36.4% in the supine position (p=0.871). Conclusion: Our report shows an improvement in oxygen saturation and airflow restriction related to the placement of the patient in the prone position. Also, we observed a mild enhancement in hemodynamic variables. The data shown is relevant because early identification of the more severe cases could help anticipate the clinical progression using the therapeutic oxygen measures necessary to avoid the disease's fatal progression. |
format | Online Article Text |
id | pubmed-8843056 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Published by Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-88430562022-02-15 HP05: Diagnostic and prognostic assessment in respiratory and hemodynamic changes related to prone position in COVID-19 patients López-Viñas, L. Roy-Vallejo, E. Rocío-Martín, E. De La Rosa Santiago, E. Zamora-García, E. Galván-Román, J.M. Wix-Ramos, R. Clin Neurophysiol Article Objective: One of the most relevant findings of COVID-19 is the respiratory damage that leads to an impairment in tissue oxygenation during the course of the disease. To study this disease's physiopathology, we have analyzed the respiratory patterns and the hemodynamic variations related to postural changes in inpatients with COVID-19. Methods: We performed a prospective study including 11 polygraph and hemodynamic studies from inpatients admitted for COVID-19 who benefited from positional changes. To assess the respiratory parameters, we conducted polygraph studies. To evaluate the hemodynamic variables, we used a thoracic electrical bioimpedance. Results: We observed a minimum oxygen saturation median of 85.00% (IQR: 7.00) in the supine position vs 91.00% (IQR: 8.00) in the prone position (p=0.173). The airflow restriction in the supine position was 2.70% (IQR: 6.55) vs 1.55% (IQR: 2.80) in the prone position (p=0.383). We observed a slight tendency to decrease in all parameters in the prone position concerning the hemodynamic variables, although they were no statistically significant. We show a decrease in vascular resistance mean in the prone position, being 18.2% vs 36.4% in the supine position (p=0.871). Conclusion: Our report shows an improvement in oxygen saturation and airflow restriction related to the placement of the patient in the prone position. Also, we observed a mild enhancement in hemodynamic variables. The data shown is relevant because early identification of the more severe cases could help anticipate the clinical progression using the therapeutic oxygen measures necessary to avoid the disease's fatal progression. Published by Elsevier B.V. 2022-03 2022-02-14 /pmc/articles/PMC8843056/ http://dx.doi.org/10.1016/j.clinph.2021.11.012 Text en Copyright © 2021 Published by Elsevier B.V. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article López-Viñas, L. Roy-Vallejo, E. Rocío-Martín, E. De La Rosa Santiago, E. Zamora-García, E. Galván-Román, J.M. Wix-Ramos, R. HP05: Diagnostic and prognostic assessment in respiratory and hemodynamic changes related to prone position in COVID-19 patients |
title | HP05: Diagnostic and prognostic assessment in respiratory and hemodynamic changes related to prone position in COVID-19 patients |
title_full | HP05: Diagnostic and prognostic assessment in respiratory and hemodynamic changes related to prone position in COVID-19 patients |
title_fullStr | HP05: Diagnostic and prognostic assessment in respiratory and hemodynamic changes related to prone position in COVID-19 patients |
title_full_unstemmed | HP05: Diagnostic and prognostic assessment in respiratory and hemodynamic changes related to prone position in COVID-19 patients |
title_short | HP05: Diagnostic and prognostic assessment in respiratory and hemodynamic changes related to prone position in COVID-19 patients |
title_sort | hp05: diagnostic and prognostic assessment in respiratory and hemodynamic changes related to prone position in covid-19 patients |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843056/ http://dx.doi.org/10.1016/j.clinph.2021.11.012 |
work_keys_str_mv | AT lopezvinasl hp05diagnosticandprognosticassessmentinrespiratoryandhemodynamicchangesrelatedtopronepositionincovid19patients AT royvallejoe hp05diagnosticandprognosticassessmentinrespiratoryandhemodynamicchangesrelatedtopronepositionincovid19patients AT rociomartine hp05diagnosticandprognosticassessmentinrespiratoryandhemodynamicchangesrelatedtopronepositionincovid19patients AT delarosasantiagoe hp05diagnosticandprognosticassessmentinrespiratoryandhemodynamicchangesrelatedtopronepositionincovid19patients AT zamoragarciae hp05diagnosticandprognosticassessmentinrespiratoryandhemodynamicchangesrelatedtopronepositionincovid19patients AT galvanromanjm hp05diagnosticandprognosticassessmentinrespiratoryandhemodynamicchangesrelatedtopronepositionincovid19patients AT wixramosr hp05diagnosticandprognosticassessmentinrespiratoryandhemodynamicchangesrelatedtopronepositionincovid19patients |