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Pre-exposure prophylaxis as an opportunity for engagement in HIV prevention among South African adolescents

Pre-exposure prophylaxis (PrEP) offers a potential biomedical strategy to reduce HIV incidence among adolescent populations disproportionately affected by HIV. There is limited evidence on the social and clinical implications, including engagement in HIV prevention efforts, of PrEP for South African...

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Autores principales: LoVette, Ashleigh, Kuo, Caroline, Giovenco, Danielle, Hoare, Jacqueline, Underhill, Kristen, Operario, Don
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843204/
https://www.ncbi.nlm.nih.gov/pubmed/35135437
http://dx.doi.org/10.1080/17290376.2021.2016479
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author LoVette, Ashleigh
Kuo, Caroline
Giovenco, Danielle
Hoare, Jacqueline
Underhill, Kristen
Operario, Don
author_facet LoVette, Ashleigh
Kuo, Caroline
Giovenco, Danielle
Hoare, Jacqueline
Underhill, Kristen
Operario, Don
author_sort LoVette, Ashleigh
collection PubMed
description Pre-exposure prophylaxis (PrEP) offers a potential biomedical strategy to reduce HIV incidence among adolescent populations disproportionately affected by HIV. There is limited evidence on the social and clinical implications, including engagement in HIV prevention efforts, of PrEP for South African adolescents, who face high HIV risk. We conducted a mixed-methods study in Western Cape, South Africa from 2015 to 2016. Adolescents (N = 35) aged 16–17 and clinical service providers working with adolescents (N = 25) were recruited from community and clinic settings. Adolescents and service providers completed a survey about their overall perceptions of PrEP and completed interviews guided by semi-structured protocols. We performed descriptive analysis of quantitative data using SPSS and thematic analysis of qualitative data using NVivo. The majority of adolescents endorsed future PrEP use for themselves and partners, and all clinical service providers endorsed future PrEP use for sexually active adolescents. Both adolescents and service providers identified PrEP as an opportunity to engage youth as active participants in HIV prevention. Service providers also viewed PrEP as a potential mechanism for shifting life trajectories. Findings from this study enhance our understanding of the considerations needed to engage adolescents and clinical service providers in the roll-out of oral PrEP in South Africa.
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spelling pubmed-88432042022-02-15 Pre-exposure prophylaxis as an opportunity for engagement in HIV prevention among South African adolescents LoVette, Ashleigh Kuo, Caroline Giovenco, Danielle Hoare, Jacqueline Underhill, Kristen Operario, Don SAHARA J Research Article Pre-exposure prophylaxis (PrEP) offers a potential biomedical strategy to reduce HIV incidence among adolescent populations disproportionately affected by HIV. There is limited evidence on the social and clinical implications, including engagement in HIV prevention efforts, of PrEP for South African adolescents, who face high HIV risk. We conducted a mixed-methods study in Western Cape, South Africa from 2015 to 2016. Adolescents (N = 35) aged 16–17 and clinical service providers working with adolescents (N = 25) were recruited from community and clinic settings. Adolescents and service providers completed a survey about their overall perceptions of PrEP and completed interviews guided by semi-structured protocols. We performed descriptive analysis of quantitative data using SPSS and thematic analysis of qualitative data using NVivo. The majority of adolescents endorsed future PrEP use for themselves and partners, and all clinical service providers endorsed future PrEP use for sexually active adolescents. Both adolescents and service providers identified PrEP as an opportunity to engage youth as active participants in HIV prevention. Service providers also viewed PrEP as a potential mechanism for shifting life trajectories. Findings from this study enhance our understanding of the considerations needed to engage adolescents and clinical service providers in the roll-out of oral PrEP in South Africa. Taylor & Francis 2022-02-08 /pmc/articles/PMC8843204/ /pubmed/35135437 http://dx.doi.org/10.1080/17290376.2021.2016479 Text en © 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
LoVette, Ashleigh
Kuo, Caroline
Giovenco, Danielle
Hoare, Jacqueline
Underhill, Kristen
Operario, Don
Pre-exposure prophylaxis as an opportunity for engagement in HIV prevention among South African adolescents
title Pre-exposure prophylaxis as an opportunity for engagement in HIV prevention among South African adolescents
title_full Pre-exposure prophylaxis as an opportunity for engagement in HIV prevention among South African adolescents
title_fullStr Pre-exposure prophylaxis as an opportunity for engagement in HIV prevention among South African adolescents
title_full_unstemmed Pre-exposure prophylaxis as an opportunity for engagement in HIV prevention among South African adolescents
title_short Pre-exposure prophylaxis as an opportunity for engagement in HIV prevention among South African adolescents
title_sort pre-exposure prophylaxis as an opportunity for engagement in hiv prevention among south african adolescents
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843204/
https://www.ncbi.nlm.nih.gov/pubmed/35135437
http://dx.doi.org/10.1080/17290376.2021.2016479
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