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Pharmacodynamics and pharmacokinetics of PLGA-based doxorubicin-loaded implants for tumor therapy

The traditional systemic chemotherapy through intravenous infusion of doxorubicin (DOX) has many side effects. The aim of this study was to develop a PLGA-based DOX-loaded implant and to evaluate the efficacy and drug metabolism distribution of the implant in intratumoral chemotherapy for osteosarco...

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Detalles Bibliográficos
Autores principales: He, Peng, Xu, Shenglin, Guo, Zehao, Yuan, Peng, Liu, Yulei, Chen, Yu, Zhang, Tiantian, Que, Yukang, Hu, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843208/
https://www.ncbi.nlm.nih.gov/pubmed/35147071
http://dx.doi.org/10.1080/10717544.2022.2032878