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Prevalence and associated factors of HIV-TB co-infection among HIV patients: a retrospective Study

BACKGROUND: TB/HIV co-infection is a major public health problem in many parts of the world. But the prevalence of co-infection was varies among countries. This study was designed to assess prevalence of TB/HIV co-infection and to determine its factors. METHODS: A retrospective study was done among...

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Autor principal: Zeru, Melkamu A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Makerere Medical School 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843304/
https://www.ncbi.nlm.nih.gov/pubmed/35222561
http://dx.doi.org/10.4314/ahs.v21i3.7
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author Zeru, Melkamu A
author_facet Zeru, Melkamu A
author_sort Zeru, Melkamu A
collection PubMed
description BACKGROUND: TB/HIV co-infection is a major public health problem in many parts of the world. But the prevalence of co-infection was varies among countries. This study was designed to assess prevalence of TB/HIV co-infection and to determine its factors. METHODS: A retrospective study was done among HIV-positive patients at Hiwot Fana hospital from December, 2014 to 2018. The study participants were selected by simple random sampling. Patients with incomplete chart reviews were excluded and demographic, clinical and laboratory information were analyzed using SPSS and STATA. Uni-vitiate and bivariate logistic regressions were applied. RESULTS: Five hundred fourteen patients were enrolled in this study. Of these, 187(37.4%) had TB. Bivariate logistic analysis showed that HIV patients with regards to marital status[AOR = 2.6; 95%CI = 1.19–2.89], education status [AOR = 3.74; 95%CI = 2.47–5.66], weight less than 50kg [AOR = 2.54; 95% CI = 1.35 – 4.81], CD4 level < 200cells/mm(3) [AOR = 4.57; 95%CI = 2.38– 6.86] and patient who were at WHO clinical stage III [AOR = 7.8; 95%CI = 5.15 – 8.55] were significantly associated with TB/HIV co-infection. CONCLUSION: The prevalence of TB among HIV patients was high and predicted by marital, education status, weight, CD4 cell count and WHO clinical stage III.
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spelling pubmed-88433042022-02-24 Prevalence and associated factors of HIV-TB co-infection among HIV patients: a retrospective Study Zeru, Melkamu A Afr Health Sci Articles BACKGROUND: TB/HIV co-infection is a major public health problem in many parts of the world. But the prevalence of co-infection was varies among countries. This study was designed to assess prevalence of TB/HIV co-infection and to determine its factors. METHODS: A retrospective study was done among HIV-positive patients at Hiwot Fana hospital from December, 2014 to 2018. The study participants were selected by simple random sampling. Patients with incomplete chart reviews were excluded and demographic, clinical and laboratory information were analyzed using SPSS and STATA. Uni-vitiate and bivariate logistic regressions were applied. RESULTS: Five hundred fourteen patients were enrolled in this study. Of these, 187(37.4%) had TB. Bivariate logistic analysis showed that HIV patients with regards to marital status[AOR = 2.6; 95%CI = 1.19–2.89], education status [AOR = 3.74; 95%CI = 2.47–5.66], weight less than 50kg [AOR = 2.54; 95% CI = 1.35 – 4.81], CD4 level < 200cells/mm(3) [AOR = 4.57; 95%CI = 2.38– 6.86] and patient who were at WHO clinical stage III [AOR = 7.8; 95%CI = 5.15 – 8.55] were significantly associated with TB/HIV co-infection. CONCLUSION: The prevalence of TB among HIV patients was high and predicted by marital, education status, weight, CD4 cell count and WHO clinical stage III. Makerere Medical School 2021-09 /pmc/articles/PMC8843304/ /pubmed/35222561 http://dx.doi.org/10.4314/ahs.v21i3.7 Text en © 2021 Zeru MA. https://creativecommons.org/licenses/by/4.0/Licensee African Health Sciences. This is an Open Access article distributed under the terms of the Creative commons Attribution License (https://creativecommons.org/licenses/BY/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Articles
Zeru, Melkamu A
Prevalence and associated factors of HIV-TB co-infection among HIV patients: a retrospective Study
title Prevalence and associated factors of HIV-TB co-infection among HIV patients: a retrospective Study
title_full Prevalence and associated factors of HIV-TB co-infection among HIV patients: a retrospective Study
title_fullStr Prevalence and associated factors of HIV-TB co-infection among HIV patients: a retrospective Study
title_full_unstemmed Prevalence and associated factors of HIV-TB co-infection among HIV patients: a retrospective Study
title_short Prevalence and associated factors of HIV-TB co-infection among HIV patients: a retrospective Study
title_sort prevalence and associated factors of hiv-tb co-infection among hiv patients: a retrospective study
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843304/
https://www.ncbi.nlm.nih.gov/pubmed/35222561
http://dx.doi.org/10.4314/ahs.v21i3.7
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