Obatoclax inhibits SARS-CoV-2 entry by altered endosomal acidification and impaired cathepsin and furin activity in vitro

Coronavirus disease 2019 (COVID-19) caused by the emerging severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has set off a global pandemic. There is an urgent unmet need for safe, affordable, and effective therapeutics against COVID-19. In this regard, drug repurposing is considered as a...

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Detalles Bibliográficos
Autores principales: Mao, Binli, Le-Trilling, Vu Thuy Khanh, Wang, Kai, Mennerich, Denise, Hu, Jie, Zhao, Zhenyu, Zheng, Jiaxin, Deng, Yingying, Katschinski, Benjamin, Xu, Shilei, Zhang, Guiji, Cai, Xuefei, Hu, Yuan, Wang, Jianwei, Lu, Mengji, Huang, Ailong, Tang, Ni, Trilling, Mirko, Lin, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Coronaviruses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843317/
https://www.ncbi.nlm.nih.gov/pubmed/34989664
http://dx.doi.org/10.1080/22221751.2022.2026739

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843317/
https://www.ncbi.nlm.nih.gov/pubmed/34989664
http://dx.doi.org/10.1080/22221751.2022.2026739

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