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Mechanism for the attenuation of neutrophil and complement hyperactivity by MSC exosomes

Complements and neutrophils are two key players of the innate immune system that are widely implicated as drivers of severe COVID-19 pathogenesis, as evident by the direct correlation of respiratory failure and mortality with elevated levels of terminal complement complex C5b-9 and neutrophils. In t...

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Detalles Bibliográficos
Autores principales: Loh, Jia Tong, Zhang, Bin, Teo, Joey Kay Hui, Lai, Ruenn Chai, Choo, Andre Boon Hwa, Lam, Kong-Peng, Lim, Sai Kiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Society for Cell & Gene Therapy. Published by Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843421/
https://www.ncbi.nlm.nih.gov/pubmed/35177337
http://dx.doi.org/10.1016/j.jcyt.2021.12.003

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