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Mechanism for the attenuation of neutrophil and complement hyperactivity by MSC exosomes
Complements and neutrophils are two key players of the innate immune system that are widely implicated as drivers of severe COVID-19 pathogenesis, as evident by the direct correlation of respiratory failure and mortality with elevated levels of terminal complement complex C5b-9 and neutrophils. In t...
Autores principales: | Loh, Jia Tong, Zhang, Bin, Teo, Joey Kay Hui, Lai, Ruenn Chai, Choo, Andre Boon Hwa, Lam, Kong-Peng, Lim, Sai Kiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Society for Cell & Gene Therapy. Published by Elsevier Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843421/ https://www.ncbi.nlm.nih.gov/pubmed/35177337 http://dx.doi.org/10.1016/j.jcyt.2021.12.003 |
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