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Cleaved CDCP1 marks the spot: a neoepitope for RAS-driven cancers

A challenge in cancer treatment is targeting cancer cells while sparing normal cells. Thus, identifying cancer-specific neoepitopes is an active research area. Neoepitopes are generated by the accumulation of mutations; however, deadly cancer types, including pancreatic cancer, have a low mutational...

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Detalles Bibliográficos
Autores principales: Donahue, Katelyn L., Pasca di Magliano, Marina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843638/
https://www.ncbi.nlm.nih.gov/pubmed/35166242
http://dx.doi.org/10.1172/JCI157168