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β-Catenin signaling in hepatocellular carcinoma

Deregulated Wnt/β-catenin signaling is one of the main genetic alterations in human hepatocellular carcinoma (HCC). Comprehensive genomic analyses have revealed that gain-of-function mutation of CTNNB1, which encodes β-catenin, and loss-of-function mutation of AXIN1 occur in approximately 35% of hum...

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Detalles Bibliográficos
Autores principales:	Xu, Chuanrui, Xu, Zhong, Zhang, Yi, Evert, Matthias, Calvisi, Diego F., Chen, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843739/ https://www.ncbi.nlm.nih.gov/pubmed/35166233 http://dx.doi.org/10.1172/JCI154515

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