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Bardoxolone Methyl Ameliorates Compression-Induced Oxidative Stress Damage of Nucleus Pulposus Cells and Intervertebral Disc Degeneration Ex Vivo

Intervertebral disc degeneration (IDD) is the main cause of low back pain, and little is known about its molecular and pathological mechanisms. According to reports, excessive compression is a high-risk factor for IDD; compressive stress can induce oxidative stress in nucleus pulposus (NP) cells dur...

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Detalles Bibliográficos
Autores principales:	Tian, Yueyang, Duan, Jiaqi, Cao, Yang, Zhou, Huichao, Diwan, Ashish D, Tu, Ji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843873/ https://www.ncbi.nlm.nih.gov/pubmed/35178384 http://dx.doi.org/10.3389/fbioe.2021.814040

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