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Polyphenol Extracts from Grape Seeds and Apple Can Reactivate Latent HIV-1 Transcription through Promoting P-TEFb Release from 7SK snRNP

The principal barrier for the eradication of HIV/AIDS is the virus latency. One of the effective strategies so called “shock and kill” is to use latency-reversing agents (LRAs) to activate the latent HIV reservoirs and then combine them with the highly active antiretroviral therapy (HAART) to eradic...

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Detalles Bibliográficos
Autores principales: Wang, Cong, Wang, Huiru, Pan, Zhenrui, Wu, Jun, Guo, Yafei, Zhang, Jing, Xiang, Zixun, Lu, Wei, Xue, Yuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843978/
https://www.ncbi.nlm.nih.gov/pubmed/35178129
http://dx.doi.org/10.1155/2022/6055347