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Blockading a new NSCLC immunosuppressive target by pluripotent autologous tumor vaccines magnifies sequential immunotherapy

The presence of multiple immunosuppressive targets and insufficient activation and infiltration of cytotoxic T lymphocytes (CTLs) allow tumor cells to escape immune surveillance and disable anti-PD-1/PD-L1 immunotherapy. Nanobiotechnology-engineered autologous tumor vaccines (ATVs) that were camoufl...

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Detalles Bibliográficos
Autores principales: Wu, Hong, Li, Hongyan, Liu, Yiqiang, Liang, Jingchen, Liu, Qianshi, Xu, Zhigang, Chen, Zhongzhu, Zhang, Xia, Zhang, Kun, Xu, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843980/
https://www.ncbi.nlm.nih.gov/pubmed/35224304
http://dx.doi.org/10.1016/j.bioactmat.2021.10.048