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Blockading a new NSCLC immunosuppressive target by pluripotent autologous tumor vaccines magnifies sequential immunotherapy
The presence of multiple immunosuppressive targets and insufficient activation and infiltration of cytotoxic T lymphocytes (CTLs) allow tumor cells to escape immune surveillance and disable anti-PD-1/PD-L1 immunotherapy. Nanobiotechnology-engineered autologous tumor vaccines (ATVs) that were camoufl...
Autores principales: | Wu, Hong, Li, Hongyan, Liu, Yiqiang, Liang, Jingchen, Liu, Qianshi, Xu, Zhigang, Chen, Zhongzhu, Zhang, Xia, Zhang, Kun, Xu, Chuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
KeAi Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843980/ https://www.ncbi.nlm.nih.gov/pubmed/35224304 http://dx.doi.org/10.1016/j.bioactmat.2021.10.048 |
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