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The Cardiovascular System in Heat Stroke
In June 2021, western Canada experienced an unprecedented heat wave, breaking dozens of temperature records. As a result, the region had a significant uptick in sudden deaths, emergency department visits, and hospital admissions. Under thermal stress, the human body achieves heat dissipation through...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843991/ https://www.ncbi.nlm.nih.gov/pubmed/35198932 http://dx.doi.org/10.1016/j.cjco.2021.10.002 |
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author | Marchand, Miles Gin, Kenneth |
author_facet | Marchand, Miles Gin, Kenneth |
author_sort | Marchand, Miles |
collection | PubMed |
description | In June 2021, western Canada experienced an unprecedented heat wave, breaking dozens of temperature records. As a result, the region had a significant uptick in sudden deaths, emergency department visits, and hospital admissions. Under thermal stress, the human body achieves heat dissipation through evaporation of sweat and increased cutaneous blood flow. When these mechanisms are overwhelmed, the core body temperature rises, which leads to heat stroke, a life-threatening syndrome of hyperthermia and central nervous system dysfunction in the setting of an environmental thermal load. Heat dissipation relies on an intact cardiovascular system to dilate cutaneous vasculature and increase cardiac output. Individuals with impaired cardiovascular function have a limited ability to increase stroke volume, cardiac output, and blood flow to the skin, increasing the risk of heat stroke. In turn, these patients, whose cardiac condition is already compromised, are susceptible to cardiovascular complications of heat stroke, including arrhythmias, myocardial ischemia, heart failure, shock, and sudden death. Indeed, the majority of excess deaths during heat waves are cardiovascular in origin, highlighting the impact the cardiovascular system has on the development of heat stroke, and vice versa. This review summarizes the current understanding of the interaction between the cardiovascular system and heat stroke, including the pathophysiology, cardiovascular complications, and treatment. |
format | Online Article Text |
id | pubmed-8843991 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-88439912022-02-22 The Cardiovascular System in Heat Stroke Marchand, Miles Gin, Kenneth CJC Open Review In June 2021, western Canada experienced an unprecedented heat wave, breaking dozens of temperature records. As a result, the region had a significant uptick in sudden deaths, emergency department visits, and hospital admissions. Under thermal stress, the human body achieves heat dissipation through evaporation of sweat and increased cutaneous blood flow. When these mechanisms are overwhelmed, the core body temperature rises, which leads to heat stroke, a life-threatening syndrome of hyperthermia and central nervous system dysfunction in the setting of an environmental thermal load. Heat dissipation relies on an intact cardiovascular system to dilate cutaneous vasculature and increase cardiac output. Individuals with impaired cardiovascular function have a limited ability to increase stroke volume, cardiac output, and blood flow to the skin, increasing the risk of heat stroke. In turn, these patients, whose cardiac condition is already compromised, are susceptible to cardiovascular complications of heat stroke, including arrhythmias, myocardial ischemia, heart failure, shock, and sudden death. Indeed, the majority of excess deaths during heat waves are cardiovascular in origin, highlighting the impact the cardiovascular system has on the development of heat stroke, and vice versa. This review summarizes the current understanding of the interaction between the cardiovascular system and heat stroke, including the pathophysiology, cardiovascular complications, and treatment. Elsevier 2021-10-12 /pmc/articles/PMC8843991/ /pubmed/35198932 http://dx.doi.org/10.1016/j.cjco.2021.10.002 Text en © 2021 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Marchand, Miles Gin, Kenneth The Cardiovascular System in Heat Stroke |
title | The Cardiovascular System in Heat Stroke |
title_full | The Cardiovascular System in Heat Stroke |
title_fullStr | The Cardiovascular System in Heat Stroke |
title_full_unstemmed | The Cardiovascular System in Heat Stroke |
title_short | The Cardiovascular System in Heat Stroke |
title_sort | cardiovascular system in heat stroke |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8843991/ https://www.ncbi.nlm.nih.gov/pubmed/35198932 http://dx.doi.org/10.1016/j.cjco.2021.10.002 |
work_keys_str_mv | AT marchandmiles thecardiovascularsysteminheatstroke AT ginkenneth thecardiovascularsysteminheatstroke AT marchandmiles cardiovascularsysteminheatstroke AT ginkenneth cardiovascularsysteminheatstroke |