Synthetic virions reveal fatty acid-coupled adaptive immunogenicity of SARS-CoV-2 spike glycoprotein

SARS-CoV-2 infection is a major global public health concern with incompletely understood pathogenesis. The SARS-CoV-2 spike (S) glycoprotein comprises a highly conserved free fatty acid binding pocket (FABP) with unknown function and evolutionary selection advantage(1,2). Deciphering FABP impact on...

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Detalles Bibliográficos
Autores principales: Staufer, Oskar, Gupta, Kapil, Hernandez Bücher, Jochen Estebano, Kohler, Fabian, Sigl, Christian, Singh, Gunjita, Vasileiou, Kate, Yagüe Relimpio, Ana, Macher, Meline, Fabritz, Sebastian, Dietz, Hendrik, Cavalcanti Adam, Elisabetta Ada, Schaffitzel, Christiane, Ruggieri, Alessia, Platzman, Ilia, Berger, Imre, Spatz, Joachim P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844029/
https://www.ncbi.nlm.nih.gov/pubmed/35165285
http://dx.doi.org/10.1038/s41467-022-28446-x

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