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Dynamic FMR1 granule phase switch instructed by m6A modification contributes to maternal RNA decay

Maternal RNA degradation is critical for embryogenesis and is tightly controlled by maternal RNA-binding proteins. Fragile X mental-retardation protein (FMR1) binds target mRNAs to form ribonucleoprotein (RNP) complexes/granules that control various biological processes, including early embryogenesi...

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Detalles Bibliográficos
Autores principales: Zhang, Guoqiang, Xu, Yongru, Wang, Xiaona, Zhu, Yuanxiang, Wang, Liangliang, Zhang, Wenxin, Wang, Yiru, Gao, Yajie, Wu, Xuna, Cheng, Ying, Sun, Qinmiao, Chen, Dahua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844045/
https://www.ncbi.nlm.nih.gov/pubmed/35165263
http://dx.doi.org/10.1038/s41467-022-28547-7