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Targeted deletion of the RNA-binding protein Caprin1 leads to progressive hearing loss and impairs recovery from noise exposure in mice
Cell cycle associated protein 1 (Caprin1) is an RNA-binding protein that can regulate the cellular post-transcriptional response to stress. It is a component of both stress granules and neuronal RNA granules and is implicated in neurodegenerative disease, synaptic plasticity and long-term memory for...
Autores principales: | Nolan, Lisa S., Chen, Jing, Gonçalves, Ana-Cláudia, Bullen, Anwen, Towers, Emily R., Steel, Karen P., Dawson, Sally J., Gale, Jonathan E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844073/ https://www.ncbi.nlm.nih.gov/pubmed/35165318 http://dx.doi.org/10.1038/s41598-022-05657-2 |
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