Cargando…
Rebalance of the Polyamine Metabolism Suppresses Oxidative Stress and Delays Senescence in Nucleus Pulposus Cells
Intervertebral disk degeneration (IDD) is a major cause of low back pain that becomes a prevalent age-related disease. However, the pathophysiological processes behind IDD are rarely known. Here, we used bioinformatics analysis based on the microarray datasets (GSE34095) to identify the differential...
Autores principales: | Che, Hui, Ma, Cheng, Li, He, Yu, Fenglei, Wei, Yifan, Chen, Hailong, Wu, Jun, Ren, Yongxin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8844099/ https://www.ncbi.nlm.nih.gov/pubmed/35178160 http://dx.doi.org/10.1155/2022/8033353 |
Ejemplares similares
-
Difluoromethylornithine rebalances aberrant polyamine ratios in Snyder–Robinson syndrome
por: Stewart, Tracy Murray, et al.
Publicado: (2023) -
PLK1 Mitigates Intervertebral Disc Degeneration by Delaying Senescence of Nucleus Pulposus Cells
por: Zhang, Zhenlei, et al.
Publicado: (2022) -
Senescence of Nucleus Pulposus Chondrocytes in Human Intervertebral Discs
por: Kim, Ki-Won, et al.
Publicado: (2008) -
Inhibition of the P53/P21 Pathway Attenuates the Effects of Senescent Nucleus Pulposus Cell‐Derived Exosomes on the Senescence of Nucleus Pulposus Cells
por: Chen, Chang‐chun, et al.
Publicado: (2020) -
p16 deficiency attenuates intervertebral disc degeneration by adjusting oxidative stress and nucleus pulposus cell cycle
por: Che, Hui, et al.
Publicado: (2020)